지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 1996.1
- 수록면
- 130 - 134 (5page)
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초록· 키워드
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The incidence and clinical features of allergic rhinitis vary as the way of life changes with the development of industry. The aim of this study is to reevaluate the clinical characteristics of allergic rhinitis in Seoul, Korea. A prospective study using a questionnaire, physical findings and in vivo and in vitro tests results was performed in 1,775 patients with allergic rhinitis living in or around Seoul. Allergic rhinitis was most common in the second decade, while its onset was most common in the first decade. In more than half of patients, nasal obstruction was the chief complaint among four major symptoms. Patients with perennial symptoms exceeded those with seasonal symptoms in number, at a ratio of 3:1. Forty percent of patients had a family history of allergic diseases. The color of the turbinate mucosa was pinkish in most patients and only 21.7% showed typically pale, edematous mucosa. The number of eosinophils in nasal secretion and in blood and total serum IgE level were significantly higher in allergic rhinitis patients compared to nonallergic subjects ; however, the proportion of patients with eosinophilia and high IgE level was low, which represents low sensitivity. The common offending allergens were house dust mites, cat fur, dog hair and mugwort in order of frequency. Most patients revealed positive skin test reactions for multiple allergens and only 6.5% of patients demonstrated pure pollinosis. The predominance of chronic nasal obstruction as a presenting symptom and the pinkish mucosal color indicate that late phase reaction is more important for chronic and persistent symptoms than acute phase reaction. Perennial type of allergic rhinitis far exceeds seasonal type from the view point of both symptomatic seasons and offending allergens. Laboratory test results including eosinophil counts in blood and nasal secretions and serum IgE level could be used only as adjunctive tools due to their low sensitivity.
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