초록·
키워드
오류제보하기
-Abstract- The miniumm inhibitory concentration (MIC) of tetracycline, doxycycline, erythromycin and streptomycin against 246 clinical isolates of Ureaplasma urealyticum were compared with those of antibiotics by a broth dilution method with growth and metabolic inhibition test, Isolation rates of Ureaplasma urealyticum from patients with vaginitis, cirvicitis, pelvic inflammatory diseases, cervical carcinoma and others were 49.3%, 57.2%, 44.2%, 53.5%, and 51.9%, respectively and the mean isolation rates are 52.2%. Color changing units (ccu) of ureaplasma from the tested specimens were 10⁴ ccu/ml (27.2%), 10³ccu/ml (19.9%), 10²ccu/ml (15%), 10¹ccu/ml (12.3%), 10⁵ccu/ml (11.8%), 10⁶ccu/ml (8.1%), and 10⁷ccu/ml (6.5%), respectively. MIC₅₀ of tetracycline, doxycycline, erythromycin and streptomycin against isolated strains of ureaplasma were 15µg/ml, 3.75µg/ml, 3.75µg/ml, and 1.86µg/ml, respectively, and MIC₉₀ of those antibiotics were 120µg/ml, 60µg/ml, 7.5µg/ml, and 7.5µg/ml, respectively. Isolation rates of resistant strains of ureaplasma to tetracycline, doxycycline, erythromycin and streptomycin were 76%, 50.4%, 24%, and 14.2%, respectively. Thirty percent of th isolates were multiple drug resistant to tetracycline and doxycycline, 6.5% were resistant to tetracycline and streptomycin, 5.7% were resistant to doxycycline, and streptomycin, and 2.8% were resistant to erythromycin and streptomycin. Two percent of the isolates were multiple drug resistant to doxycycline, erythromycin and streptomycin, 1.2% of the isolates were resistant to tetracycline, doxycycline, and erythromycin, and 1.2% of isolates were resistant to tetracycline, doxycycline, sand streptomycin.