The effect of long working hours on developing type 2 diabetes in adults with prediabetes: The Kangbuk Samsung Cohort Study

Eunhye Seo; Yesung Lee; Eunchan Mun; Dae Hoon Kim; Youshik Jeong; Jaehong Lee; Jinsook Jeong; Woncheol Lee

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저자정보: Eunhye Seo (Sungkyunkwan University School of Medicine) Yesung Lee (Sungkyunkwan University School of Medicine) Eunchan Mun (Sungkyunkwan University School of Medicine) Dae Hoon Kim (Sungkyunkwan University School of Medicine) Youshik Jeong (Sungkyunkwan University School of Medicine) Jaehong Lee (Sungkyunkwan University School of Medicine) Jinsook Jeong (Sungkyunkwan University School of Medicine) Woncheol Lee (Sungkyunkwan University School of Medicine)

저널정보: 대한직업환경의학회 대한직업환경의학회지 대한직업환경의학회지 제34권 제2호

발행연도: 2022.3

수록면: 1 - 11 (11page)

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Background: Long working hours are known to account for approximately one-third of the total expected work-related diseases, and much interest and research on long working hours have recently been conducted. Additionally, as the prevalence of prediabetes and the high-risk group for diabetes are increasing worldwide, interest in prediabetes is also rising. However, few studies have addressed the development of type 2 diabetes and long working hours in prediabetes. Therefore, the aim of this longitudinal study was to evaluate the relationship between long working hours and the development of diabetes in prediabetes.
Methods: We included 14,258 prediabetes participants with hemoglobinA1c (HbA1c) level of 5.7 to 6.4 in the Kangbuk Samsung Cohort Study. According to a self-reported questionnaire, we evaluated weekly working hours, which were categorized into 35–40, 41–52, and ＞ 52 hours. Development of diabetes was defined as an HbA1c level ≥ 6.5%. Hazard ratios (HRs) and 95% confidence intervals (CIs) for the development of diabetes were estimated using Cox proportional hazards analyses with weekly working 35–40 hours as the reference.
Results: During a median follow-up of 3.0 years, 776 participants developed diabetes (incidence density, 1.66 per 100 person-years). Multivariable-adjusted HRs of development of diabetes for weekly working ＞ 52 hours compared with working 35–40 hours were 2.00 (95% CI: 1.50–2.67). In subgroup analyses by age (＜ 40 years old, ≥ 40 years old), sex (men, women), and household income (＜ 6 million KRW, ≥ 6 million KRW), consistent and significant positive associations were observed in all groups.
Conclusions: In our large-scale longitudinal study, long working hours increases the risk of developing diabetes in prediabetes patients.

#Longitudinal studies #Working hours #Workload #Diabetes mellitus #Prediabetes #Prediabetic state

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