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논문 기본 정보

자료유형
학술저널
저자정보
저널정보
한국생약학회 생약학회지(Korean Journal of Pharmacognosy) 생약학회지 제16권 제1호
발행연도
1985.3
수록면
18 - 25 (8page)

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초록· 키워드

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Experimental studies were conducted to investigate for the effect of Tongkyu-tang on analgesic, antipyretic, sedative, anti-inflammatory, isolated ileum and antihistamine actions. Tongkyu-Tang was composed of sixteen crude drugs including Astr agali Radix, which has been used for the treatment of common cold, headache, rhinitis, nasal obstruction, rhincospasm, etc. The following results have been obtained; analgesic and antipyretic actions were obtained. Prolonged action against the hypnotic duration of pentobarbital were significantiy noted in mice. Anti-inflammatory effects in the paw edema induced by 1% carrageenin and 1% dextran were significantly shown in rats. Spontaneous motilities of isolated ileum of mice were strongly suppressed, and contractions of isolated ileum of mice and guinea-pigs induced by acetylcholine chloride, barium chloride and histamine were remarkably inhibited. Antihistamine actions were noted. Considering the above experimental results, it is suggested that effects of Tongkyu tang based on the Oriental Medical References were similarly consistent with the actual experimental results.

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