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논문 기본 정보

자료유형
학술저널
저자정보
(Yonsei University College of Dentistry) (Yonsei University College of Dentistry) (Yonsei University College of Dentistry)
저널정보
대한치의학회 Journal of Korean Dental Science Journal of korean dental science Vol.15 No.2
발행연도
수록면
121 - 131 (11page)

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초록· 키워드

Ameloblastoma is the most representative epithelial odontogenic tumor in the craniofacial region. Through several studies on Ameloblastoma that have been conducted so far, we have been able to get closer to the reality of Ameloblastoma. However, groundbreaking insight into the pathophysiology of Ameloblastoma has not yet been provided. This review assessed three aspects of five recently published papers on Ameloblastoma: cancer stem cells, calcium signaling, and tumor microenvironment, and compared them with previous studies on tumor physiology, including cancer. In addition, the characteristics of Ameloblastoma revealed by the experimental methods presented in the currently published five papers provide the possibility of Ameloblastoma as a study model in general tumor or cancer studies. Furthermore, the mechanisms of action of the chemicals identified in the studies support their potential as candidates for the second-line treatment of Ameloblastoma.
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목차

  1. Introduction
  2. Population of Cancer Stem Cells and Wnt Signaling in Ameloblastoma
  3. Calcium Signaling and Collective Invasion of Ameloblastoma
  4. Tumor Microenvironment of Ameloblastoma
  5. Conclusion and Perspectives
  6. References

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