개인구독
소속 기관이 없으신 경우, 개인 정기구독을 하시면 저렴하게
논문을 무제한 열람 이용할 수 있어요.
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2022.3
- 수록면
- 1 - 5 (5page)
- DOI
- 10.1186/s42649-022-00078-x
이용수
초록· 키워드
오류제보하기
The compact smooth muscle 10S myosin II is a type of a monomer with folded tail and the heads bending back to interact with each other. This inactivated form is associated with regulatory and enzymatic activities affecting myosin processivity with actin filaments as well as ATPase activity. Phosphorylation by RLC can however, shuttle myosin from the inhibited 10S state to an activated 6S state, dictating the equilibrium. Multiple studies contributed by TEM have provided insights in the structural understanding of the 10S form. However, it is only recently that the true potential of Cryo-EM in deciphering the intramolecular interactions of 10S myosin state has been realized. This has led to an influx of new revelations on the 10S inactivation, unfolding mechanism and association in various diseases. This study reviews the gradual development in the structural interpretation of 10S species from TEM to Cryo-EM era. Furthermore, we discuss the utility of Cryo-EM in future myosin 10S studies and its contribution to human health.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Facility for high resolution cryo-electron microscopy of biological macromolecules at Korea Basic Science Institute
Biodesign
2017 .09
-
Alteration of Stress Fiber in Fibroblastic Reticular Cells via Lymphotoxin β Receptor Stimulation is Associated with Myosin
생명과학회지
2015 .05
-
Advanced Cryo-Electron Microscopy Technology: High Resolution Structure of Macromolecules
한국현미경학회지
2016 .01
-
Toward High-Resolution Cryo-Electron Microscopy: Technical Review on Microcrystal-Electron Diffraction
한국현미경학회지
2017 .01
-
초저온 전자현미경법을 통한 고분해능 생물분자 구조분석
진공이야기
2017 .12
-
Practices in cryo-EM single particle analysis data processing: data transfer between RELION and cryoSPARC
Biodesign
2024 .06
-
Corrigendum: Grid selection strategy for highresolution cryo-EM
Biodesign
2020 .01
-
Molecular Structure of Muscle Filaments Determined by Electron Microscopy
한국현미경학회지
2017 .01
-
The Nobel Prize in Chemistry 2017: High-Resolution Cryo-Electron Microscopy
한국현미경학회지
2017 .01
-
Correlative Live-cell Microscopy and Cryo-electron Tomography
한국미생물학회 학술대회논문집
2018 .04
-
Structural Analysis of Virus Capsid Proteins Using Cryo-electron Microscopy Single Particle Analysis
한국미생물학회 학술대회논문집
2017 .04
-
Grid selection strategy for high-resolution cryo-EM
Biodesign
2020 .01
-
Performance test of a Cryo-TMP combination pump
한국진공학회 학술발표회초록집
2016 .08
-
Myosin18B predicts favorable prognosis of cutaneous squamous-cell carcinoma
Genes & Genomics
2021 .01
-
The cryo-vacuum system of east neutral beam injector
한국진공학회 학술발표회초록집
2016 .08
-
Prokaryotic transcription regulation by the nascent RNA elements
Biodesign
2020 .01
-
Some living eukaryotes during and after scanning electron microscopy
한국현미경학회지
2021 .12
-
Cryo-Transmission Electron Microscopy in Korean Society of Microscopy
한국현미경학회지
2017 .01
-
Real-Time Measurement of the Liquid Amount in Cryo-Electron Microscopy Grids Using Laser Diffraction of Regular 2-D Holes of the Grids
Molecules and Cells
2020 .01
-
Cryo-EM as a powerful tool for drug discovery: recent structural based studies of SARS-CoV-2
한국현미경학회지
2021 .09
이 논문의 저자 정보
최근 본 자료
댓글(0)
0