지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2022.6
- 수록면
- 578 - 584 (7page)
- DOI
- 10.3349/ymj.2022.63.6.578
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초록· 키워드
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Purpose: To investigate the effect of regular monitoring of pulmonary function and ventilatory status on the initiation of non-invasiveventilation (NIV) between patients who were routinely monitored before receiving NIV and those who were not.
Materials and Methods: This retrospective cohort study included subjects with Duchenne muscular dystrophy (DMD) who first receivedNIV between 2010 and 2019. The subjects were assigned to either the regular-follow-up (REG) group or the non-REG group,according to their follow-up status, before initiating NIV. We compared the number of emergent cases, the results of nocturnal ventilatorymonitoring, and the pulmonary function of each group at initial ventilatory support.
Results: In total, 73 subjects were enrolled in the REG group and 47 subjects in the non-REG group. There were significantly moreemergency cases due to respiratory insufficiency in the non-REG group (12/47, 25.5%) than in the REG group (3/73, 4.1%). At thetime of initial ventilatory support, hypoventilatory symptoms were more common and relatively severe in the non-REG group(37/47, 78.7%) than in the REG group (18/73, 24.7%). The average age at initial ventilatory support of the non-REG group was 2.15years older than that of the subjects in the REG group. Moreover, subjects who were not regularly monitored exhibited greater deteriorationin pulmonary function compared to those who were regularly followed up.
Conclusion: Regular evaluation of pulmonary function and ventilatory status before the onset of ventilatory insufficiency is crucialto reduce the risk of patients with DMD requiring emergency care due to ventilatory insufficiency.
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