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학술저널
저자정보
배혜경 ((재) 서울의과학연구소) 홍정미 (서울의과학연구소) 김영진 ((재) 서울의과학연구소) 이경렬 (서울의과학연구소(용인)) 이경원 (서울의과학연구소) 최성진 (연세대학교) 어영 (연세대학교)
저널정보
연세대학교 의과대학 Yonsei Medical Journal Yonsei Medical Journal 제63권 제8호
발행연도
2022.8
수록면
717 - 723 (7page)
DOI
10.3349/ymj.2022.63.8.717

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Purpose: The prevalence of Group B Streptococcus (GBS) colonization in pregnant Korean women is increasing; however, nation wide studies are lacking. Therefore, we aimed to analyze regional colonization rates and antimicrobial susceptibility for GBS inpregnant Korean women through a nationwide survey. Materials and Methods: From January 2018 to December 2020, data from the Seoul Clinical Laboratories on vaginal swab cultureswere retrospectively analyzed to detect maternal GBS carriers. Each swab specimen was inoculated onto a 5% blood agar plateand incubated at 35°C–37°C in a 5% CO2 incubator for 24 h. GBS isolates were identified using a Microflex MALDI Biotyper. Anti microbial susceptibility tests were performed using the Vitek 2 automated system. Results: The overall nationwide GBS colonization rate in pregnant Korean women was found to be 10.6% (3578/33721). The ma ternal GBS colonization rates ranged from 10.5%–10.8% over the 3-year study period. The GBS colonization rates by province, indescending order, were as follows: Jeolla-do, 13.2%; Gangwon-do, 12.0%; Chungcheong-do, 11.8%; Gyeonggi-do, 11.3%; Seoul,10.2%; and Gyeongsang-do, 9.6%. During the study period, the resistance rates against chloramphenicol, levofloxacin, clindamy cin, erythromycin, and tetracycline were 2.6%–2.7%, 18.2%–19.6%, 33.4%–35.7%, 35.6%–36.8%, and 50.5%–53.3%, respectively. Conclusion: In pregnant Korean women, GBS colonization rates were in the range of 9.6%–13.2%, with Gyeongsang-do being thelowest and Jeolla-do the highest. The resistance rate against clindamycin was high (33.4%–35.7%). GBS colonization rates duringpregnancy should be studied nationwide according to the Centers for Disease Control and Prevention-recommended guidelineswith periodic antimicrobial resistance monitoring.

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