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학술저널
저자정보
Carla Maria Irene Quarato (Department of Medical and Surgical Sciences Institute of Respiratory DiseasesUniversity of Foggia) Mariapia Venuti (Department of Medical and Surgical Sciences Institute of Respiratory DiseasesUniversity of Foggia) Lucia Dimitri (Unit of PathologyIRCCS Fondazione Casa Sollievo della Sofferenza) Donato Lacedonia (Department of Medical and Surgical Sciences Institute of Respiratory DiseasesUniversity of Foggia) Anna Simeone (Department of Radiology IRCCS Fondazione Casa Sollievo della Sofferenza) Antonio Mirijello (Department of Internal MedicineIRCCS Fondazione Casa Sollievo della Sofferenza) Salvatore De Cosmo (Department of Internal MedicineIRCCS Fondazione Casa Sollievo della Sofferenza) Evaristo Maiello (Unit of OncologyIRCCS Fondazione Casa Sollievo della Sofferenza) Marco Taurchini (Unit of Thoracic SurgeryIRCCS Fondazione Casa Sollievo della Sofferenza) Giulia Scioscia (Department of Medical and Surgical Sciences Institute of Respiratory DiseasesUniversity of Foggia) Maria Pia Foschino Barbaro (Department of Medical and Surgical Sciences Institute of Respiratory DiseasesUniversity of Foggia) Massimiliano Copetti (Unit of BiostatisticsIRCCS Fondazione Casa Sollievo della Sofferenza) Marco Sperandeo (Unit of Interventional and Diagnostic Ultrasound Department of Internal Medicine IRCCS Fondazione)
저널정보
대한초음파의학회 ULTRASONOGRAPHY ULTRASONOGRAPHY Vol.41 No.1
발행연도
2022.1
수록면
93 - 105 (13page)
DOI
10.14366/usg.21021

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Purpose: The aim of this study was to assess whether new-generation shear wave elastography (SWE) is suitable for the characterization of lung subpleural lesions.Methods: In total, 190 consecutive patients with subpleural lung lesions received ultrasonography and SWE. Patients with suspected malignancy underwent ultrasound-guided transthoracic needle biopsy. Final diagnoses were made on the basis of patients’ clinical course, microbiological studies, and histological results. SWE was also performed in 25 healthy volunteers.Results: We found no statistically significant differences in stiffness between lung carcinomas, lung metastases, and pneumonia (P=0.296) or between different histological types of lung cancer (P=0.393). Necrosis was associated with reduced stiffness in pneumonia. Excluding necrotic lesions, pneumonia showed higher stiffness than lung carcinomas (2.95±0.68 m/s vs. 2.60±0.54 m/s, P=0.006). Chronic pneumonia showed increased stiffness (3.03±0.63 m/s), probably due to the presence of fibrotic tissue on histology. Pleural effusion was associated with a statistically significant reduction in stiffness, both in lung carcinomas (P=0.004) and lung metastases (P=0.002). The presence of air in healthy lung tissue may lead to incorrect speed estimates due to shear wave reflection (very high values, 14.64±2.19 m/s).Conclusion: Transthoracic SWE could not distinguish lung malignancy from pneumonia, or between different histological types of lung carcinomas. In particular, SWE seems unable to resolve the clinical dilemma of chronic subpleural consolidations.

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