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논문 기본 정보

자료유형
학술저널
저자정보
Koh Seok Young (Department of Radiology Seoul National University Hospital Seoul Korea.) 이승현 (서울대학교병원) Lee Seul Bi (Department of Radiology Seoul National University Hospital Seoul Korea.) Cho Yeon Jin (Department of Radiology Seoul National University Hospital Seoul Korea.) Choi Young Hun (Department of Radiology Seoul National University College of Medicine Seoul National University Hos) 천정은 (서울대학교) 김우선 (서울대학교)
저널정보
대한초음파의학회 ULTRASONOGRAPHY ULTRASONOGRAPHY Vol.41 No.2
발행연도
2022.4
수록면
325 - 334 (10page)
DOI
10.14366/usg.21072

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Purpose: This study aimed to assess the feasibility of shear-wave elastography (SWE) for assessing the testicular involvement of hematologic malignancies in children and young adults.Methods: Eight patients (mean age, 11.0 years; range, 0.8 to 20 years) with biopsy-confirmed testicular involvement of hematologic malignancy between January 2018 and December 2020 were retrospectively evaluated. Multiparametric ultrasound examinations, including grayscale, color Doppler ultrasonography (CDUS), and SWE, were performed. Stiffness was measured in the involved testicular area and contralateral normal parenchyma. If there was bilateral testicular involvement, the stiffness of the involved area and the adjacent normal echoic parenchyma was measured on one testis. The Mann-Whitney U test was used to compare stiffness values.Results: On grayscale, the testicular lesions were noted as a solitary mass in one patient, multiple lesions in four patients, and diffuse involvement in three patients. On CDUS and SWE, all patients demonstrated increased vascularity, and the stiffness of the involved area was higher than the values of normal parenchyma (the involved area vs. normal parenchyma, 11.6 kPa [3.9-20.2 kPa] vs. 2.9 kPa [1.1-3.7 kPa], P=0.003). The ratio of stiffness between the involved area and normal parenchyma was 3.4, ranging from 1.9 to 5.1. One patient showed decreased stiffness on follow-up SWE after treatment (affected testis vs. normal testis: initial, 13.8 vs. 3.2 kPa; 1 year later, 2.2 vs. 2.4 kPa).Conclusion: Increased testicular stiffness on SWE in children and young adults with hematologic malignancies suggests the possibility of testicular involvement.

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