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논문 기본 정보

자료유형
학술저널
저자정보
박성용 (계요병원 정신건강의학과) 박원명 (가톨릭대학교) 우영섭 (가톨릭대학교) 정종현 (가톨릭대학교 의과대학 정신건강의학교실) 윤보현 (국립나주병원) 서정석 (중앙대학교) 추일한 (조선대학교) 양찬모 (원광대학교) 김원 (인제대학교 의과대학 상계백병원 정신건강의학과) 이정구 (인제대학교 의과대학 해운대백병원 정신건강의학과) 심세훈 (순천향대학교 의과대학 천안병원 정신건강의학과) 정명훈 (한림대학교 의과대학 한림대학교성심병원 정신건강의학과) 전덕인 (한림대학교) 김문두 (제주대학교) 손인기 (계요병원 정신건강의학과)
저널정보
대한신경정신의학회 신경정신의학 신경정신의학 제61권 제4호
발행연도
2022.11
수록면
274 - 280 (7page)

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Objectives The safety and tolerability of drugs are very important to ensure compliance and ef ficacy in the treatment of bipolar disorders. An expert opinion survey was conducted on treat ment strategies in various special clinical situations, such as patients with significant weight gain, reporting characteristic drug side effects, low drug adherence, pregnant and reproductive wom en, and genetic counseling. Methods A written survey that addressed treatment strategies related to safety and tolerability was prepared. The survey focused on significant weight gain, characteristic drug side effects, low drug adherence, treatment of pregnant and reproductive women, and genetic counseling. Eighty-seven experts in the review committee completed the survey Results In the case of weight gain occurring during drug treatment, it was considered preferable to replace the treatment drug with a drug that caused less weight gain, such as lamotrigine, aripip razole, or ziprasidone. If there was a significant weight gain due to the treatment drug, it was con sidered preferable to intervene as soon as possible. In the case of hyperprolactinemia, it was con sidered preferable to change the drug. It was recommended that the drug beto discontinued in case of a benign rash as seen in patients treated with lamotrigine. For improving drug adherence, there was an increased preference for long-acting injections. It was also opined that antipsychot ics should be used with great caution in pregnant or reproductive women. Conclusion Treatment strategies in various clinical situations related to the safety and tolerability of drugs for bipolar disorder have been described. It is hoped that this information would be use ful in practical clinical situations.

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