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논문 기본 정보

자료유형
학술저널
저자정보
Hwa Young Yu (Konyang University College of Medicine) Min Woo Lee (Konyang University College of Medicine) Jung Tae Kim (Konyang University College of Medicine) 이성철 (건양대학교) 이영훈 (건양대학교)
저널정보
대한안과학회 Korean Journal of Ophthalmology Korean Journal of Ophthalmology 제36권 제3호
발행연도
2022.6
수록면
274 - 281 (8page)
DOI
10.3341/kjo.2021.0174

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Purpose: To evaluate the difference in each retinal layer thickness in central retinal vein occlusion (CRVO) with resolved macularedema after intravitreal antivascular endothelial growth factor injection and normal contralateral eyes..Methods: Patients with ischemic and nonischemic CRVO whose macular edema resolved after intravitreal antivascular endothelialgrowth factor injections and did not recur for at least 6 months, and a normal contralateral eye were enrolled. Eachretinal layer thickness between CRVO and normal contralateral eyes was compared according to Early Treatment DiabeticRetinopathy Study subfields using spectral domain optical coherence tomography.Results: The thicknesses of outer nuclear layer, photoreceptor layer, and retinal pigment epithelium in central ring, ganglioncell layer, inner plexiform layer, outer nuclear layer, and photoreceptor layer in the inner ring, and ganglion cell layer in theouter ring of CRVO eyes were significantly thinner than those of normal contralateral eyes (all p < 0.05). Whereas, inner nuclearlayer and outer plexiform layer thicknesses in central ring of CRVO eyes were 23.86 ± 8.8 and 25.76 ± 7.6 μm, respectively,which was significantly thicker than those of normal contralateral eyes (19.52 ± 7.7 and 22.76 ± 6.5 μm; p = 0.019 and p = 0.043,respectively). Additionally, the mean best-corrected visual acuity of CRVO eyes were significantly correlated with photoreceptorlayer thickness in central ring (p = 0.005).Conclusions: In CRVO eyes with resolved macular edema, the outer retinal layers were thinner as well as inner retinal layers,whereas inner plexiform layer and outer nuclear layer were thicker than normal fellow eyes. Additionally, photoreceptor layerthickness in foveal area had a significant impact on visual acuity in CRVO.

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