지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2022.9
- 수록면
- 227 - 245 (19page)
- DOI
- 10.1007/s13206-022-00069-w
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초록· 키워드
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M13 bacteriophage is a promising biomolecule with unique biochemical and structural traits (e.g., high aspect ratio, 2700 copies of identical coat proteins covering the phage surface) that can also be programmable, making it a versatile material for bio-nano and biomimetic applications. Although M13 bacteriophage is mostly known as a carrier in the phage display screening process, pioneers have used the phage’s properties to develop the virus into a bionanomaterial that can be used for various applications. This study reviews M13 bacteriophage-based bio-nano systems derived from the structural and biochemical properties of M13 bacteriophage for both bio-nano and material science applications. Two major approaches regarding the fabrication of the bio-nano systems are introduced: surface engineering of individual M13 bacteriophage into single bio-nano templates and self-assembly of M13 bacteriophages into bio-nano matrices. Various genetic engineering and chemical engineering methods are reported for the surface engineering of M13 bacteriophage, which enables the bionanomaterial to have a wide range of functionalities. The bio-nano and material science applications of the self-assembled bio-nano matrices are also examined in this study. These complex engineered M13 bacteriophage-based matrices are capable of guiding a new generation of bionanomaterials for bio-nano and material science applications.
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