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논문 기본 정보

자료유형
학술저널
저자정보
Shafqat Musheer (Bach Christian Hospital) Jo Ji Hoon (Kosin University Gospel Hospital Kosin University College of Medicine) 문형환 (고신대학교) 최영일 (고신대학교) Shin Dong Hoon (Kosin University Gospel Hospital Kosin University College of Medicine)
저널정보
고신대학교 의과대학 고신대학교 의과대학 학술지 고신대학교 의과대학 학술지 제37권 제2호
발행연도
2022.6
수록면
107 - 118 (12page)
DOI
10.7180/kmj.22.108

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초록· 키워드

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Alcohol-related liver disease (ALD) has become the major cause of liver transplantation (LT) in Korea, and is currently the most common cause of LT in Europe and the United States. Although, ALD is one of the most common indications for LT, it is traditionally not considered as an option for patients with ALD due to organ shortages and concerns about relapse. To select patients with terminal liver disease due to ALD for transplants, most LT centers in the United States and European countries require a 6-month sober period before transplantation. However, Korea has a different social and cultural background than Western countries, and most organ transplants are made from living donors, who account for approximately twice as many procedures as deceased donors. Most LT centers in Korea do not require a specific period of sobriety before transplantation in patients with ALD. As per the literature, 8%?20% of patients resume alcohol consumption 1 year after LT, and this proportion increases to 30%?40% at 5 years post-LT, among which 10%?15% of patients resume heavy drinking. According to previous studies, the risk factors for alcohol relapse after LT are as follows: young age, poor familial and social support, family history of alcohol use disorder, previous history of alcohol-related treatment, shorter abstinence before LT, smoking, psychiatric disorders, irregular follow-up, and unemployment. Recognition of the risk factors, early detection of alcohol consumption after LT, and regular follow-up by a multidisciplinary team are important for improving the short- and long-term outcomes of LT patients with ALD.

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