Hepatitis A Outbreak in a Facility for the Disabled, Gyeonggi Province, Korea: An Epidemiological Investigation

Chang Yeonhwa; Kim Chanhee; Kim Nayoung; Kim Joon Jai; Lee Heeyoung

doi:10.3961/jpmph.21.349

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자료유형: 학술저널

저자정보: Chang Yeonhwa (Infectious Disease Control Center Gyeonggi Provincial Government Suwon Korea) Kim Chanhee (Infectious Disease Control Center Gyeonggi Provincial Government Suwon Korea) Kim Nayoung (Regional Centers for Disease Control and Prevention Korea Disease Control and Prevention Agency) Kim Joon Jai (Infectious Disease Control Center Gyeonggi Provincial Government Suwon Korea) Lee Heeyoung (Korea Center for Preventive Medicine and Public Health Seoul National UnivHospital Seongnam Korea)

저널정보: 대한예방의학회 예방의학회지 예방의학회지 제54권 제5호

발행연도: 2021.9

수록면: 370 - 375 (6page)

DOI: 10.3961/jpmph.21.349

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Objectives: The number of cases of hepatitis A virus (HAV) infections has sharply increased in Korea, especially among young adults. In this study, an HAV outbreak in a facility for disabled people was investigated, and we found epidemiological differences both between 2 different generations and between generally abled and disabled groups.Methods: We analyzed the incubation period and attack rate of an HAV outbreak and investigated the prevalence of HAV antibodies among the staff and residents of a facility for the disabled. We performed a retrospective cohort study during the HAV outbreak, which lasted from February 8 to 25, 2019, including examinations of HAV antibody tests and post-exposure HAV vaccination for the staff or residents of the facility.Results: There were 9 confirmed cases in 2 staff members and 7 residents. Among 53 people (30 staff and 23 residents), except for the 9 confirmed cases and 1 staff member with a known history of HAV infection, HAV seroprevalence was seen in 16.7% of the staff under 40 years of age and 95.2% of those over 40 years of age, while the corresponding rates in the residents were 0.0% and 58.8%, respectively.Conclusions: This result implies that it is necessary to prioritize HAV vaccination for vulnerable groups and workers of residential care facilities.

#Hepatitis A #Immunization #Vaccination #Seroepidemiologic studies

참고문헌 (23)

참고문헌 신청

Lin KY / 2017 / Hepatitis A virus infection and hepatitis A vaccination in human immunodeficiency virus-positive patients : a review / World J Gastroenterol 23(20):3589~3606

Kanda T / 2010 / Analysis of 5’ nontranslated region of hepatitis A viral RNA genotype I from South Korea: comparison with disease severities / PLoS One 5(12):e15139

Lee DY / 2021 / Nationwide seroprevalence of hepatitis A in South Korea from 2009 to 2019 / PLoS One 16(2):e0245162

Martin A / 2006 / Hepatitis A virus: from discovery to vaccines / Hepatology 43(2 Suppl 1):S164~S172

Cristina J / 2007 / Genetic variability and molecular evolution of hepatitis A virus / Virus Res 127(2):151~157

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