지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 27 - 34 (8page)
이용수
초록· 키워드
오류제보하기
The cytoplasm in mammalian cells is a battlefield between the host and invading microbes. Both the living organisms have evolved unique strategies for their survival. The host utilizes a specialized autophagy system, xenophagy, for the clearance of invading pathogens, whereas bacteria secrete proteins to defend and escape from the host xenophagy. Several molecules have been identified and their structural investigation has enabled the comprehension of these mechanisms at the molecular level. In this review, we focus on one example of host autophagy and the other of bacterial defense: the autophagy receptor, NDP52, in conjunction with the sugar receptor, galectin-8, plays a critical role in targeting the autophagy machinery against Sal-monella; and the cysteine protease, RavZ secret-ed by Legionella pneumophila cleaves the LC3-PE on the phagophore membrane. The structure-function relationships of these two examples and the directions of future research will be dis-cussed.
목차
등록된 정보가 없습니다.
참고문헌 (67)
참고문헌 신청
Behrends, C. / 2012 / Receptor proteins in selective autophagy / Int. J. Cell Biol. 2012:673290
Boyle, K.B. / 2013 / The role of 'eat-me' signals and autophagy cargo receptors in innate immunity / Curr. Opin. Microbiol. 16:339~348
Celli, J. / 2012 / LRSAM1, an E3 Ubiquitin ligase with a sense for bacteria / Cell Host. Microbe 12:735~736
Chen, W. / 2011 / Unusual regioversatility of acetyltransferase Eis, a cause of drug resistance in XDR-TB / Proc. Natl. Acad. Sci. USA 108:9804~9808
Choy, A. / 2012 / The Legionella effector RavZ inhibits host autophagy through irreversible Atg8 deconjugation / Science 338:1072~1076
Boyle, K.B. / 2013 / The role of 'eat-me' signals and autophagy cargo receptors in innate immunity / Curr. Opin. Microbiol. 16:339~348
Celli, J. / 2012 / LRSAM1, an E3 Ubiquitin ligase with a sense for bacteria / Cell Host. Microbe 12:735~736
Chen, W. / 2011 / Unusual regioversatility of acetyltransferase Eis, a cause of drug resistance in XDR-TB / Proc. Natl. Acad. Sci. USA 108:9804~9808
Choy, A. / 2012 / The Legionella effector RavZ inhibits host autophagy through irreversible Atg8 deconjugation / Science 338:1072~1076
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Overview of the Minireviews on Autophagy
Molecules and Cells
2018 .01
-
The autophagy research in electron microscopy
한국현미경학회지
2019 .01
-
Molecular Mechanisms of Host-microbe Interactions
한국미생물학회 학술대회논문집
2020 .10
-
The Role of Autophagy in Systemic Metabolism and Human-Type Diabetes
Molecules and Cells
2018 .01
-
Autophagy and Oral Cancer
생명과학회지
2017 .08
-
Autophagy in Mycobacterium abscessus Infection
JOURNAL OF BACTERIOLOGY AND VIROLOGY
2017 .09
-
Host Ubiquitin System Regulating Machineries from SARS-CoV-2 and Legionella
한국미생물학회 학술대회논문집
2021 .08
-
Autophagy and Longevity
Molecules and Cells
2018 .01
-
Emerging Paradigm of Crosstalk between Autophagy and the Ubiquitin-Proteasome System
Molecules and Cells
2017 .12
-
Lipopolysaccharide (LPS)-Induced Autophagy Is Responsible for Enhanced Osteoclastogenesis
Molecules and Cells
2017 .11
-
Autophagy Dysregulation and Obesity-Associated Pathologies
Molecules and Cells
2018 .01
-
Autophagy Is Pro-Senescence When Seen in Close-Up, but Anti-Senescence in Long-Shot
Molecules and Cells
2017 .09
-
Host Immune Pathways to Mycobacterium tuberculosis Infection
JOURNAL OF BACTERIOLOGY AND VIROLOGY
2024 .09
-
Diversity of bacterial communities and occurrence of Legionella pneumophila in three water treatment plants
한국분석과학회 학술대회
2024 .11
-
Ubiquilin 1 Targets Invading Salmonella typhimurium to the Autophagy Pathway
한국미생물학회 학술대회논문집
2022 .10
-
Protein and RNA Quality Control by Autophagy in Plant Cells
Molecules and Cells
2019 .01
-
Effects of in vitro vitamin D treatment on function of T cells and autophagy mechanisms in high-fat diet-induced obese mice
Nutrition Research and Practice
2021 .12
-
Effects of in vitro vitamin D treatment on function of T cells and autophagy mechanisms in high-fat diet-induced obese mice
Nutrition Research and Practice
2021 .12
-
PKA regulates autophagy through lipolysis during fasting
Molecules and Cells
2024 .01
-
Outer Membrane Protein A of Acinetobacter baumannii Inhibits Host Xenophagy through Dephosphorylation of the AMPK Pathway a CAMKK2-dependent
한국미생물학회 학술대회논문집
2022 .10
이 논문의 저자 정보
최근 본 자료
댓글(0)
0