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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.6
- 수록면
- 1,970 - 1,978 (9page)
- DOI
- https://doi.org/10.1016/j.net.2020.12.006
이용수
초록· 키워드
오류제보하기
The aim of this study was to optimize the target, moderator, and collimator (TMC) in a neutron beamgenerator for the accelerator-based BNCT (A-BNCT) system. The optimization employed the Monte CarloNeutron and Photon (MCNP) simulation. The optimal geometry for the target was decided as the onewith the highest neutron flux among nominates, which were called as angled, rib, and tube in this study.
The moderator was optimized in terms of consisting material to produce appropriate neutron energydistribution for the treatment. The optimization of the collimator, which wrapped around the target, wascarried out by deciding the material to effectively prevent the leakage radiations. As results, characteristicof the neutron beam from the optimized TMC was compared to the recommendation by the InternationalAtomic Energy Agent (IAEA). The tube type target showed the highest neutron flux amongnominates. The optimal material for the moderator and collimator were combination of Fluental(Al203þAlF3) with 60Ni filter and lead, respectively. The optimized TMC satisfied the IAEA recommendationssuch as the minimum production rate of epithermal neutrons from thermal neutrons: that was2.5 times higher. The results can be used as source terms for shielding designs of treatment rooms.
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참고문헌 (18)
참고문헌 신청
Jeffrey A. Coderre / 1999 / The Radiation Biology of Boron Neutron Capture Therapy / Radiation Research 151(1):1
H. Koivunoro / 2015 / Biokinetic analysis of tis-sue boron(10B)concentrations of glioma patients treated with BNCT in Finland / Appl. Radiat. Isot 106:189~194
T. Watanabe / 2016 / Comparison of the pharmacokinetics between l-BPA and l-FBPA using the same adminis-tration dose and protocol : a validation study for the theranostic approach using [18 F]-l-FBPA positron emission tomography in boron neutron capture ther-apy / BMC Canc 16:859
M. Monshizadeh / 2015 / MCNP design of thermal and ep-ithermal neutron beam for BNCT at the Isfahan MNSR / Prog. Nucl. Energy 83:427~432
J. Esposito / 2009 / Be target development for the accelerator-based SPES-BNCT facility at INFN Legnaro / Appl. Radiat. Isot 67:7~8
H. Koivunoro / 2015 / Biokinetic analysis of tis-sue boron(10B)concentrations of glioma patients treated with BNCT in Finland / Appl. Radiat. Isot 106:189~194
T. Watanabe / 2016 / Comparison of the pharmacokinetics between l-BPA and l-FBPA using the same adminis-tration dose and protocol : a validation study for the theranostic approach using [18 F]-l-FBPA positron emission tomography in boron neutron capture ther-apy / BMC Canc 16:859
M. Monshizadeh / 2015 / MCNP design of thermal and ep-ithermal neutron beam for BNCT at the Isfahan MNSR / Prog. Nucl. Energy 83:427~432
J. Esposito / 2009 / Be target development for the accelerator-based SPES-BNCT facility at INFN Legnaro / Appl. Radiat. Isot 67:7~8
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