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논문 기본 정보

자료유형
학술저널
저자정보
Kim Gyungah (Department of Internal Medicine Asan Medical Center University of Ulsan College of Medicine Seoul K) Choi Eun-Ji (Department of Hematology Asan Medical Center University of Ulsan College of Medicine Seoul Korea.) Park Han-Seung (Department of Hematology Asan Medical Center University of Ulsan College of Medicine Seoul Korea.) Lee Jung-Hee (Department of Hematology Asan Medical Center University of Ulsan College of Medicine Seoul Korea.) Lee Je-Hwan (Department of Hematology Asan Medical Center University of Ulsan College of Medicine Seoul Korea.) Lee Kyoo-Hyung (Department of Hematology Asan Medical Center University of Ulsan College of Medicine Seoul Korea.)
저널정보
대한의학회 Journal of Korean Medical Science Journal of Korean Medical Science Vol.36 No.43
발행연도
2021.11
수록면
1 - 5 (5page)
DOI
10.3346/jkms.2021.36.e306

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초록· 키워드

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Immune thrombocytopenia (ITP) is an autoimmune condition characterized by platelet destruction through antibody-mediated mechanism. ITP is one of the manifestations of a coronavirus disease, as well as an adverse event occurring after vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Several cases of ITP have been described after vaccination with two mRNA-based vaccines?BTN162b2 (Pfizer-BioNTech) and mRNA-1273 (Moderna)?against SARS-CoV-2. Herein, we report a case of ITP occurring after vaccination with ChAdOx1 adenovirus vector nCoV-19 (AstraZeneca) vaccine in Korea. A 66-year-old woman presented with multiple ecchymoses on both upper and lower extremities and gingival bleeding, appearing 3 days after receiving the first dose of ChAdOx1 nCoV19. Her laboratory results showed isolated severe thrombocytopenia without evidence of combined coagulopathy. She was diagnosed with ITP and successfully treated with high-dose dexamethasone and intravenous immunoglobulin. Clinical suspicion to identify vaccinerelated ITP is important to promptly initiate appropriate treatment.

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