지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.11
- 수록면
- 981 - 989 (9page)
- DOI
- 10.3349/ymj.2021.62.11.981
이용수
초록· 키워드
오류제보하기
Purpose: Although drug-coated balloon (DCB) treatment is known to be effective for de novo lesions, the influence of sex on angiographic and clinical outcomes remains unknown. This study aimed to investigate the angiographic and clinical impact of DCB treatment in patients with de novo coronary lesions according to sex.
Materials and Methods: A total of 227 patients successfully treated with DCB were retrospectively enrolled and divided into two groups according to sex. The primary endpoint was late lumen loss (LLL) at 6-month angiography, and the secondary endpoint was target vessel failure (TVF), which included cardiac death, target vessel myocardial infarction, target lesion revascularization, and target vessel thrombosis.
Results: The study enrolled 60 women (26.4%) and 167 men (73.6%). Compared to men, women had a smaller vessel size, larger DCB to reference vessel ratio, and more dissections after DCB treatment (55.0% vs. 37.1%, p=0.016). Women also had a significantly higher LLL compared to men (0.12±0.26 mm vs. 0.02±0.22 mm, p=0.012) at the 6-month follow-up angiography. During a median follow-up of 3.4 years (range 12.7?28.9 months), TVF was similar (women 6.7% vs. men 7.8%, p=0.944). In multivariable analysis, women were independently associated with a higher LLL.
Conclusion: LLL was higher in women, but there was no difference in TVF between women and men. Based on multivariable analysis, the women sex was an independent predictor of higher LLL (Impact of Drug-coated Balloon Treatment in de Novo Coronary Lesion; NCT04619277).
목차
등록된 정보가 없습니다.
참고문헌 (23)
참고문헌 신청
Funakoshi S / 2011 / Clinical characteristics and outcomes of Japanese women undergoing coronary revascularization therapy / Circ J 75:1358~1367
Kornowski R / 2012 / A comparative analysis of major clinical outcomes with drug-eluting stents versus bare metal stents in male versus female patients / EuroIntervention 7:1051~1059
Mehran R / 2010 / A risk score to predict bleeding in patients with acute coronary syndromes / J Am Coll Cardiol 55:2556~2566
Rao SV / 2013 / An updated bleeding model to predict the risk of post-procedure bleeding among patients undergoing percutaneous coronary intervention : a report using an expanded bleeding definition from the National Cardiovascular Data Registry CathPCI Registry / JACC Cardiovasc Interv 6:897~904
Yu J / 2016 / Sexbased differences in cessation of dual-antiplatelet therapy following percutaneous coronary intervention with stents / JACC Cardiovasc Interv 9:1461~1469
Kornowski R / 2012 / A comparative analysis of major clinical outcomes with drug-eluting stents versus bare metal stents in male versus female patients / EuroIntervention 7:1051~1059
Mehran R / 2010 / A risk score to predict bleeding in patients with acute coronary syndromes / J Am Coll Cardiol 55:2556~2566
Rao SV / 2013 / An updated bleeding model to predict the risk of post-procedure bleeding among patients undergoing percutaneous coronary intervention : a report using an expanded bleeding definition from the National Cardiovascular Data Registry CathPCI Registry / JACC Cardiovasc Interv 6:897~904
Yu J / 2016 / Sexbased differences in cessation of dual-antiplatelet therapy following percutaneous coronary intervention with stents / JACC Cardiovasc Interv 9:1461~1469
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