지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.10
- 수록면
- 509 - 533 (25page)
- DOI
- 10.3344/kjp.2021.34.4.509
이용수
초록· 키워드
오류제보하기
Background: Postherpetic neuralgia (PHN) is a refractory complication of herpes zoster (HZ). To prevent PHN, various strategies have been aggressively adopted. However, the efficacy of these strategies remains controversial. Therefore, we aimed to estimate the relative efficacy of various strategies used in clinical practice for preventing PHN using a network meta-analysis (NMA).
Methods: We performed a systematic and comprehensive search to identify all randomized controlled trials. The primary outcome was the incidence of PHN at 3 months after acute HZ. We performed both frequentist and Bayesian NMA and used the surface under the cumulative ranking curve (SUCRA) values to rank the interventions evaluated.
Results: In total, 39 studies were included in the systematic review and NMA. According to the SUCRA value, the incidence of PHN was lower in the order of continuous epidural block with local anesthetics and steroids (EPI-LSE), antiviral agents with subcutaneous injection of local anesthetics and steroids (AV + sLS), antiviral agents with intracutaenous injection of local anesthetics and steroids (AV + iLS) at 3 months after acute HZ. EPI-LSE, AV + sLS and AV + iLS were also effective in preventing PHN at 1 month after acute HZ. And paravertebral block combined with antiviral and antiepileptic agents was effective in preventing PHN at 1, 3, and 6 months.
Conclusions: The continuous epidural block with local anesthetics and steroid, antiviral agents with intracutaneous or subcutaneous injection of local anesthetics and a steroid, and paravertebral block combined with antiviral and antiepileptic agents are effective in preventing PHN.
목차
등록된 정보가 없습니다.
참고문헌 (132)
참고문헌 신청
Kawai K / 2014 / Systematic review of incidence and complications of herpes zoster : towards a global perspective / BMJ Open 4:e004833
Yawn BP / 2013 / The global epidemiology of herpes zoster / Neurology 81:928~930
Johnson RW / 2015 / Herpes zoster epidemiology, management, and disease and economic burden in Europe : a multidisciplinary perspective / Ther Adv Vaccines 3:109~120
Erskine N / 2017 / A systematic review and meta-analysis on herpes zoster and the risk of cardiac and cerebrovascular events / PLoS One 12:e0181565
Forbes HJ / 2016 / A systematic review and meta-analysis of risk factors for postherpetic neuralgia / Pain 157:30~54
Yawn BP / 2013 / The global epidemiology of herpes zoster / Neurology 81:928~930
Johnson RW / 2015 / Herpes zoster epidemiology, management, and disease and economic burden in Europe : a multidisciplinary perspective / Ther Adv Vaccines 3:109~120
Erskine N / 2017 / A systematic review and meta-analysis on herpes zoster and the risk of cardiac and cerebrovascular events / PLoS One 12:e0181565
Forbes HJ / 2016 / A systematic review and meta-analysis of risk factors for postherpetic neuralgia / Pain 157:30~54
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