지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.10
- 수록면
- 301 - 312 (12page)
- DOI
- 10.5125/jkaoms.2020.46.5.301
이용수
초록· 키워드
오류제보하기
In disease diagnostics and health surveillance, the use of saliva has potential because its collection is convenient and noninvasive. Over the past two decades, the development of salivary utilization for the early detection of cancer, especially oral cavity and oropharynx cancer has gained the interest of the researcher and clinician. Until recently, the oral cavity and oropharynx cancers are still having a five-year survival rate of 62%, one of the lowest in all major human cancers. More than 90% of oral cancers are oral squamous cell carcinoma (OSCC). Despite the ease of accessing the oral cavity in clinical examination, most OSCC lesions are not diagnosed in the early stage, which is suggested to be the main cause of the low survival rate. Many studies have been performed and reported more than 100 potential saliva biomarkers for OSCC. However, there are still obstacles in figuring out the reliable OSCC salivary biomarkers and the clinical application of the early diagnosis protocol. The current review article discusses the emerging issues and is hoped to raise awareness of this topic in both researchers and clinicians. We also suggested the potential salivary biomarkers that are reliable, specific, and sensitive for the early detection of OSCC.
목차
등록된 정보가 없습니다.
참고문헌 (70)
참고문헌 신청
Mishra A / 2010 / Cancer biomarkers: are we ready for the prime time? / Cancers (Basel) 2:190~208
Shield KD / 2017 / The global incidence of lip, oral cavity, and pharyngeal cancers by subsite in 2012 / CA Cancer J Clin 67:51~64
Conway DI / 2018 / The changing epidemiology of oral cancer : definitions, trends, and risk factors / Br Dent J 225:867~873
Patel RS / 2009 / Prognostic factors in the surgical treatment of patients with oral carcinoma / ANZ J Surg 79:19~22
Gupta N / 2016 / Changing Trends in oral cancer-a global scenario / Nepal J Epidemiol 6:613~619
Shield KD / 2017 / The global incidence of lip, oral cavity, and pharyngeal cancers by subsite in 2012 / CA Cancer J Clin 67:51~64
Conway DI / 2018 / The changing epidemiology of oral cancer : definitions, trends, and risk factors / Br Dent J 225:867~873
Patel RS / 2009 / Prognostic factors in the surgical treatment of patients with oral carcinoma / ANZ J Surg 79:19~22
Gupta N / 2016 / Changing Trends in oral cancer-a global scenario / Nepal J Epidemiol 6:613~619
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