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논문 기본 정보

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학술저널
저자정보
Molly Kidder (University of South Florida Health) Claudia Phen (University of Texas Southwestern Medical Center) Jerry Brown (Johns Hopkins All Children's Hospital) Kathryn Kimsey (Johns Hopkins All Children's Hospital) Benjamin Oshrine (Johns Hopkins All Children's Hospital) Sharon Ghazarian (Johns Hopkins All Children's Institute for Clinical and Translational Research) Jazmine Mateus (Johns Hopkins All Children's Institute for Clinical and Translational Research) Ernest Amankwah (Johns Hopkins All Children's Hospital) Michael Wilsey (University of South Florida Health)
저널정보
대한소아소화기영양학회 Pediatric Gastroenterology, Hepatology & Nutrition Pediatric Gastroenterology, Hepatology & Nutrition 제24권 제6호
발행연도
2021.11
수록면
546 - 554 (9page)
DOI
10.5223/pghn.2021.24.6.546

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Purpose: Malnutrition is a significant issue for pediatric patients with cancer. We sought to evaluate the effectiveness and complication rate of percutaneous endoscopic gastrostomy (PEG) placement in pediatric oncology patients. Methods: A retrospective chart review was performed on 49 pediatric oncology patients undergoing PEG placement at Johns Hopkins All Children's Hospital between 2000 and 2016. Demographic and clinical characteristics, complications, absolute neutrophil count at time of PEG placement and at time of complications, length of stay, and mortality were identified. Weight-for-age Z-scores were evaluated at time of- and six months post-PEG placement. Results: The overall mean weight-for-age Z-score improved by 0.73 (p<0.0001) from pre- (?1.11) to post- (?0.38) PEG placement. Improvement in Z-score was seen in patients who were malnourished at time of PEG placement (1.14, p<0.0001), but not in those who were not malnourished (0.32, p=0.197). Site infections were seen in 12 (24%), buried bumper syndrome in five (10%), and tube dislodgement in one (2%) patient. One patient (2%) with fever was treated for possible peritonitis. There were no cases of other major complications, including gastric perforation, gastrocolic fistula, clinically significant bleeding, or PEGrelated death documented. Conclusion: Consistent with previous studies, our data suggests a relationship between site complications (superficial wound infection, buried bumper syndrome) and neutropenia. Additionally, PEG placement appears to be an effective modality for improving nutritional status in malnourished pediatric oncology patients. However, larger prospective studies with appropriate controls and adjustment for potential confounders are warranted to confirm these findings.

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