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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.11
- 수록면
- 362 - 368 (7page)
- DOI
- https://doi.org/10.13050/foodengprog.2021.25.4.362
이용수
초록· 키워드
오류제보하기
The prevalence of obesity is steadily growing worldwide, causing several severe complications, including type 2 diabetes and cardiovascular diseases. With the importance of preventive approaches to obesity, related nutraceuticals and compounds are developing. Probiotics are attracting attention as a substance that is effective against obesity.
Among the probiotics, Lactobacillus rhamnosus Lb102 and Bifidobacterium animalis ssp. Bf141 individually has the effect of preventing metabolic syndrome, including anti-obesity. Therefore, we examined the effect of a mixture of Lactobacillus rhamnosus Lb102 and Bifidobacterium animalis ssp. Bf141. The mixture of Lactobacillus rhamnosus Lb102 (Lb102) and Bifidobacterium animalis ssp. Bf141 (Bf141) was administered to a high-fat diet (HFD, 60% kcal from fat)-induced obese mice for eight weeks. The probiotics mixture did not alter body weight, feed intake, and body adiposity, meaning the rescue of obesity was ineffective. Furthermore, there was no difference in the liver weight, which is the center of lipid synthesis. In addition, the probiotics mixture did not modify fecal lipid content, an indicator of lipid digestion and absorption. Serum triglycerides and total cholesterol levels also remained unchanged. In conclusion, these results imply that the probiotics mixture of Lb102 and Bf141 had no anti-obesity outcome in HFD-induced obese mice.
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등록된 정보가 없습니다.
참고문헌 (30)
참고문헌 신청
Alard J / 2021 / Multiple selection criteria for probiotic strains with high potential for obesity management / Nutrients 13:713
Butel M-J / 2014 / Probiotics, gut microbiota, and health / Med. Mal. Infect 44:1~8
de la Cuesta-Zuluaga J / 2018 / Higher fecal short-chain fatty acid levels are associated with gut microbiome dysbiosis, obesity, hypertension and cardiometabolic disease risk factors / Nutrients 11:51
Diehl AM / 2017 / Cause, pathogenesis, and treatment of nonalcoholic steatohepatitis / N. Engl. J. Med 377:2063~2072
Ellacott KLJ / 2010 / Assessment of feeding behavior in laboratory mice / Cell Metab 12:10~17
Butel M-J / 2014 / Probiotics, gut microbiota, and health / Med. Mal. Infect 44:1~8
de la Cuesta-Zuluaga J / 2018 / Higher fecal short-chain fatty acid levels are associated with gut microbiome dysbiosis, obesity, hypertension and cardiometabolic disease risk factors / Nutrients 11:51
Diehl AM / 2017 / Cause, pathogenesis, and treatment of nonalcoholic steatohepatitis / N. Engl. J. Med 377:2063~2072
Ellacott KLJ / 2010 / Assessment of feeding behavior in laboratory mice / Cell Metab 12:10~17
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