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논문 기본 정보

자료유형
학술저널
저자정보
Bahar Yeşil Örnek (Dr. Abdurrahman Yurtaslan Oncology Research and Training Hospital Psychiatry Departmant University) Birgül Elbozan Cumurcu (Inonu University Medicine Faculty Psychiatry Departmant) Esra Porgali Zayman (Inonu University Medicine Faculty Psychiatry Departmant)
저널정보
대한신경정신의학회 PSYCHIATRY INVESTIGATION PSYCHIATRY INVESTIGATION 제18권 제10호
발행연도
2021.10
수록면
1,018 - 1,024 (7page)
DOI
10.30773/pi.2021.0040

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Objective Functional neurogical symptom disorder (FNSD) is a somatic symptom disorder with loss of voluntary motor or sensory functions, which cannot be explained by another medical condition. The study aimed to examine the relationship of vasopressin and oxytocin in persistent type FNSD.Methods This study included 27 female patients between the ages of 20?57 who were diagnosed with FNSD according to DSM-5 and 27 healthy controls matched in terms of age and gender. Serum vasopressin and oxytocin levels were measured twice on the same day in fasting blood samples and the results were compared statistically.Results Vasopressin were lower in patients compared to controls while there was no difference between oxytocin levels. Childhood traumas were more common in patient group, and mean oxytocin level was lower in patients who exposed to childhood trauma, compared to controls. No significant difference was found between the groups in terms of vasopressin.Conclusion Changes in vasopressin and oxytocin balance in the pathogenesis of persistant FNSD, may likely to lead to physiological and behavioral consequences. Lower oxytocin levels may also be a marker of exposure to childhood trauma in FNSD. These neuropeptides plays important role in neuroendocrine balance of emotional behavior.

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