Optimal First-Line Therapy for Acute Low-Tone Sensorineural Hearing Loss

Shin Seung-Ho; Byun Sung Wan; Park Sohl; Kim Eun Hye; Kim Min Woo; 이호윤

doi:10.7874/jao.2021.00269

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저자정보: Shin Seung-Ho (Department of Otolaryngology-Head and Neck Surgery College of Medicine Ewha Womans University Seoul) Byun Sung Wan (Department of Otolaryngology-Head and Neck Surgery College of Medicine Ewha Womans University Seoul) Park Sohl (Department of Otolaryngology-Head and Neck Surgery College of Medicine Ewha Womans University Seoul) Kim Eun Hye (Department of Otolaryngology-Head and Neck Surgery College of Medicine Ewha Womans University Seoul) Kim Min Woo (Department of Otorhinolaryngology Daejeon Eulji University Medical Center Eulji University School o) 이호윤 (이화여자대학교)

저널정보: 대한청각학회 Journal of Audiology & Otology Journal of Audiology & Otology Vol.25 No.4

발행연도: 2021.10

수록면: 209 - 216 (8page)

DOI: 10.7874/jao.2021.00269

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Background and Objectives: We aimed to analyze treatment outcomes following different initial management approaches and confirm treatment regimens for acute low-tone sensorineural hearing loss (ALHL) that would yield the best results.Subjects and Methods: We retrospectively analyzed the medical records of 106 patients with ALHL who visited a university hospital’s otology clinic from March 2013 to June 2019. Pure-tone averages at the initial visit and at 2 and 4 weeks after the initial visit were evaluated.Results: Forty-nine patients were enrolled in this study; of them, 41 (83.7%) exhibited complete recovery (CR) at 2 weeks and 43 (87.8%) exhibited CR at 1 month after the initial visit. Regression analysis revealed that CR at 2 weeks after the initial visit was associated with diuretic use [Exp(B): 10.309, 95% confidence interval (CI): 1.007-100]. An initial daily low-dose steroid use was marginally significant [Exp(B): 1.042, 95% CI: 0.997-1.092; p=0.066]. Isolated diuretic use [Exp(B): 25.641, 95% CI: 1.121-90.909; p=0.039] was an independent, good prognostic factor at 1 month after the initial visit. However, other treatment regimens did not affect the final results.Conclusions: A combination of initial daily administration of ≤30 mg prednisolone plus diuretics was sufficient as the first-line treatment for ALHL. High-dose steroids and salvage intratympanic steroid injections can be applied as a second choice; however, the predicted outcome would not be good in that case.

#Hearing loss #Sudden #Meniere disease #Treatment outcome #Prognosis #Steroids

참고문헌 (28)

참고문헌 신청

Morita S / 2010 / A comparison of the short-term outcome in patients with acute low-tone sensorineural hearing loss / ORL J Otorhinolaryngol Relat Spec 72:295~299

Yoshida T / 2017 / Idiopathic sudden sensorineural hearing loss and acute low-tone sensorineural hearing loss : a comparison of the results of a nationwide epidemiological survey in Japan / Acta Otolaryngol 137:S38~S43

장진경 / 2016 / Short-Term Outcomes of Acute Low-Tone Sensorineural Hearing Loss According to Treatment Modality / Journal of Audiology & Otology 20(1):47~52

Junicho M / 2008 / Prognosis of low-tone sudden deafness-does it inevitably progress to Meniere’s disease / Acta Otolaryngol 128:304~308

Yamasoba T / 1994 / Acute low-tone sensorineural hearing loss without vertigo / Arch Otolaryngol Head Neck Surg 120:532~535

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이 논문의 저자 정보

Shin Seung-Ho

소속기관 Department of Otolaryngology-Head and Neck Surgery College of Medicine Ewha Womans University Seoul