지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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Objectives ： Although psychostimulants for suppressing appetite have indications for a short-term use, long-term prescriptions are also frequently encountered in clinical practice. The objective of this study was to overview the empirical evidence on the safety of such psychostimulants. Methods ： A rapid systematic review was conducted using existing systematic review articles or clinical guidelines developed by adopting systematic review methodology. Results ： Four systematic review articles or clinical guidelines were reviewed. Studies on the safety of diethylpropion were all short-term. Six case reports reported psychotic symptoms. Phentermine, phendimetrazine, and diethylpropion have been withdrawn in most countries due to their side effects such as drug abuse and cardiotoxicity. Long-term prescription safety for phentermine or diethylpropion was not addressed in existing clinical guidelines for pharmacological management of adult obesity. Moreover, studies on the efficacy and safety of psychostimulants in the childhood and adolescence obesity management have not been reported yet. Conclusion : The number of studies on the long-term safety of antiobesity psychostimulants prescriptions was too limited to conclude their efficacy and safety for long-term use. Thus, long-term prescriptions of antiobesity psychostimulants should be avoided and closer monitoring is needed even for short-term use of psychostimulants in subjects with mental health risk.
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등록된 정보가 없습니다.
참고문헌 (28)
참고문헌 신청
Apovian CM / 2016 / Obesity: definition, comorbidities, causes, and burden / Am J Manag Care 22(7 Suppl):s176~s185
Ministry of Health and Welfare / 2019 / Korea Health Statistics 2018 / Ministry of Health and Welfare & Korea Centers for Disease Control and Prevention
National Health Insurance Service / 2017 / A study on improvement plan for insurer’s obesity management service for improving healthy lifespan / National Health Insurance Service
Williams EP / 2015 / Overweight and Obesity: Prevalence, Consequences, and Causes of a Growing Public Health Problem / Curr Obes Rep 4:363~370
Apovian CM / 2015 / Endocrine Society. Pharmacological management of obesity: an endocrine society clinical practice guideline / J Clin Endocrinol Metab 100:342~362
Ministry of Health and Welfare / 2019 / Korea Health Statistics 2018 / Ministry of Health and Welfare & Korea Centers for Disease Control and Prevention
National Health Insurance Service / 2017 / A study on improvement plan for insurer’s obesity management service for improving healthy lifespan / National Health Insurance Service
Williams EP / 2015 / Overweight and Obesity: Prevalence, Consequences, and Causes of a Growing Public Health Problem / Curr Obes Rep 4:363~370
Apovian CM / 2015 / Endocrine Society. Pharmacological management of obesity: an endocrine society clinical practice guideline / J Clin Endocrinol Metab 100:342~362
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