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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.10
- 수록면
- 366 - 370 (5page)
- DOI
- 10.12701/yujm.2021.00899
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초록· 키워드
오류제보하기
Immune checkpoint inhibitors (ICIs) have become the main drugs for programmed cell death receptor-1 or ligand-1 expressing non-small cell lung cancer (NSCLC) combined with conventional chemotherapy. ICIs are generally more tolerable than cytotoxic chemotherapies in terms of toxicity, and ICI-related adverse events are mild and manageable. However, these drugs may lead to unexpected severe adverse events such as immune-related hematologic toxicities, which could be life-threatening. Here, a rare case of a pembrolizumab-related adverse event in a patient with NSCLC who showed early-onset hemolytic anemia and recovered by high-dose steroid and a series of plasma exchanges is reported.
목차
등록된 정보가 없습니다.
참고문헌 (17)
참고문헌 신청
Ribas A / 2012 / Tumor immunotherapy directed at PD-1 / N Engl J Med 366:2517~2519
Dobosz P / 2019 / The intriguing history of cancer immunotherapy / Front Immunol 10:2965
Mellman I / 2011 / Cancer immunotherapy comes of age / Nature 480:480~489
Michot JM / 2016 / Immune-related adverse events with immune checkpoint blockade : a comprehensive review / Eur J Cancer 54:139~148
Calvo R / 2019 / Hematological side effects of immune checkpoint inhibitors : the example of immune-related thrombocytopenia / Front Pharmacol 10:454
Dobosz P / 2019 / The intriguing history of cancer immunotherapy / Front Immunol 10:2965
Mellman I / 2011 / Cancer immunotherapy comes of age / Nature 480:480~489
Michot JM / 2016 / Immune-related adverse events with immune checkpoint blockade : a comprehensive review / Eur J Cancer 54:139~148
Calvo R / 2019 / Hematological side effects of immune checkpoint inhibitors : the example of immune-related thrombocytopenia / Front Pharmacol 10:454
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