일차성 부갑상선기능항진증으로 수술적 치료를 받은 환자들에 대한 임상적 고찰

천용일; 권현근; 정다운; 김재욱; 김성동; 신성찬; 안상정; 이진춘; 이병주; 김인주

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자료유형: 학술저널

저자정보: 천용일 (부산대학교) 권현근 (부산대학교) 정다운 (부산대학교 의학전문대학원 이비인후과학교실) 김재욱 (부산대학교병원 이비인후과) 김성동 (부산대학교병원) 신성찬 (부산대학교병원) 안상정 (성균관대학교) 이진춘 (부산대학교) 이병주 (부산대학교) 김인주 (부산대학교)

저널정보: 대한이비인후과학회 부산,울산,경남 지부회 임상이비인후과 임상이비인후과 제28권 제2호

발행연도: 2017.12

수록면: 205 - 210 (6page)

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Background and Objectives：To evaluate the accuracy of ultrasound (US), computed tomography (CT) and 99Tc sestamibi scan (MIBI) for preoperative localization of solitary parathyroid mass in patients with primary hyperparathyroidism and analyze our surgical outcomes. Materials and Methods：In a retrospective study of 57 consecutive patients with primary hyperparathyroidism, all patients underwent parathyroidectomy from Jan. 2003 through Dec. 2013. Patients were performed ultrasound, computed tomography and Technetium-99m sestamibi scan before surgery. We also reviewed serum calcium, serum parathyroid hormone (iPTH), associated symptoms and pathologic results through electronic medical records (EMR). Results：All 57 patients were enrolled and they had single solitary parathyroid mass. In final pathologic results, 45 patients had solitary parathyroid adenoma, 7 patients had nodular hyperplasia and 5 patients were diagnosed as parathyroid cancer. In adenoma and carcinoma as a single nodule, accuracy of US was 95.2% (40/42), CT was 91.7% (44/48), MIBI was 81.5% (31/38). The most common symptoms were general weakness and nausea. Interestingly, asymptomatic hypercalcemia, incidentaloma were over the half patients. Postoperative numbness was observed in 4 patients and they were treated with calcium supplementation but not persisted longer than 4th day postoperatively. Conclusions：Our results show that the combination of US, CT, MIBI has benefits for preoperative localization of parathyroid mass in primary hyperparathyroidism and parathyroidectomy was useful for patients with primary hyperparathyroidism.

#일차성 부갑상선 기능항진증· 컴퓨터단층촬영·초음파검사·99mTc-sestamibi 스캔. #Primary hyperparathyroidismㆍComputed tomographyㆍUltrasonographyㆍ99mTc-sestamibi.

참고문헌 (14)

참고문헌 신청

Welsh DA / 1898 / Concerning the parathyroid glands: A critical, anatomical, and experimental study / J Anat Physiol 32:292~307

Larsen WJ / 2001 / Human Embryology / Churchill Livingstone

Mohebati A / 2012 / Anatomy of thyroid and parathyroid glands and neurovascular relations / Clin Anat 25(1):19~31

이승원 / 2006 / 부갑상선 기능항진증을 동반한 부갑상선 선종에 대한 임상적 고찰 / 대한이비인후과학회지 두경부외과학 49(1):72~78

DeLellis RA / 2003 / Surgery of the thyroid and parathyroid glands / Saunders :571~577

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주요연구분야 의약학 > 임상의학 > 이비인후과학 의약학 > 임상의학 > 내과학

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