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학술저널
저자정보
김윤전 (서울아산병원(울산대부설)) June-Gone Kim (Department of Ophthalmology Asan Medical Center University of Ulsan College of Medicine Seoul K) 이주영 (서울아산병원(울산대부설)) 이경섭 (울산대학교) 조수근 (울산대학교) 박중열 (울산대학교) 김민선 (울산대학교) 윤영희 (울산대학교)
저널정보
대한의학회 Journal of Korean Medical Science Journal of Korean Medical Science Vol.29 No.12
발행연도
2014.12
수록면
1,699 - 1,705 (7page)

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The aim of this study was to evaluate the incidence of and risk factors for the developmentof diabetic retinopathy (DR) and progression to proliferative DR (PDR) in Korean patients. Patients diagnosed with type 2 diabetes and followed for more than 5 years at a universitybasedclinic since 2000 were consecutively enrolled in this retrospective cohort study. Basedon the DR classification at the initial and final visits, the incidence and progression of DRwas determined and patient characteristics were compared according to DR progression. Hazard ratios of each putative risk factor for DR progression were calculated with amultivariate Cox proportional hazard model. Rate of DR development and progression toPDR were 32.1/1,000 and 26.2/1,000 person-years, respectively. A longer duration ofdiabetes and higher mean HbA1c level were significant risk factors for the development ofDR. Regarding progression to PDR, higher mean HbA1c level, higher standard deviation ofHbA1c, and higher urine albumin-to-creatinine ratio were significant risk factors. The ratesof development of DR and progression to PDR in Koreans with type 2 diabetes are lowerthan those reported over the last decade. An inadequate blood glycemic control is thecommon risk factor for development and progression of DR.

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