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초록· 키워드
In this study, antioxidant (DPPH free radical scavenging activity, Nitric Oxide Scavenging activity), antimicrobial activities and bioactivematerials (polyphenolics and flavonoids compounds) of ethanol extract of leaves from Thuja orientalis (TOL) were investigated. Theethanol extract from TOL showed higher DPPH radical scavenging activity and Nitric Oxide (NO) scavenging activity than other crudeplant extract in a concentration-dependent manner. The present results suggest that the ethanol extract from TOL may be potent agent forantioxidant and thereby inhibit the pathological conditions caused by excessive generation of NO and ROS. Total phenolic content andTotal flavonoid content was 61.2±2.35 and 42.32±1.015 μg/mL in ethanol extract of TOL respectively. The result of antimicrobialeffects, we were able to confirm that ethanol extract of TOL at S. epidermidis, p. acnes and M. furfur showed the clear zone on 250, 500μg/disc concentration. The highest antimicrobial activity showed at p. ovale on 125, 250, 500 μg/disc concentration of ethanol extract ofTOL. Taken together, ethanol extract of TOL was shown to have the most potent antioxidative and antimicrobial activities and thehighest content of polyphenolic and flavonoids compounds.
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