Swine wastewater was treated using a unique sequence of ion exchange membrane bedsystem (IEBR). Organic matter and nutrient in swine wastewater was pre-treated by electron beamirradiation. The optimal dose for solubilization of organic matter in swine wastewater ranged from20 kGy to 75 kGy. The carbohydrates, proteins, and lipids were investigated as the solubilizedorganic fraction of swine wastewater and proteins and lipids mainly contained of the solubilizedorganic matter. The solubilization of organic matter in swine wastewater was affected by the combinationeffect of temperature and a dose. The average chemical oxygen demand (COD) removalefficiency under room temperature conditions was 67.1%, while that under psychrophilic conditionswas 54.6%. For removal of ammonia, the removal efficiency decreased from 63.6% at 23 C to 33.5%16.8 C. On the other hand, the removal of phosphorus was not a function of temperature. Struvitewas one of main mechanisms in anaerobic condition.