인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
DBpia AI
AI 에이전트
AI 아이디어
AI 리더
AI 뷰어
Citeasy
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지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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초록· 키워드
Introduction: Dental implants are routinely used with high success rates in generally healthy individuals. By contrast,
their use in patients with diabetes mellitus remains controversial as altered bone healing around implants has been
reported. The present study aimed to investigate the bone healing response around immediately placed titanium
implants in the rats with controlled and uncontrolled diabetes.
Materials and Methods: Twenty rats were divided into the control, insulin-treated and diabetic groups. The rats
received streptozotocin (60 mg/kg) to induce diabetes; animals in the insulin-treated group also received three units of
subcutaneous slow-release insulin. A titanium implant (1.2×3 mm) was placed in the extraction socket of the maxillary
first molar and was harvested at 2 and 4 weeks. After routine process of histologic process, section were measured for
Bone-implant contact, bone density using Image analysis program.
Results: After 2 weeks post-implantation, BCR (Bone contract ratio) of the control, the diabetic group and insulintreated
group was 42.62%, 24.55% and 27.75%, respectively. The BCR of the control was lower than the diabetic
group and insulin-treated group. After 4 weeks post-implantation, BCR (Bone contract ratio) of the control, the
diabetic group and insulin-treated group was 45.32%, 39.14% and 43.84%, respectively. Also, the results of bone
density was showed a similar pattern of the results of BCR.
Conclusion: The immediate placement of titanium implants in the maxilla of controlled diabetic rat led to a wanted
bone healing response. In conclusion, the results of this study suggest that immediate implant insertion in patients with
controlled diabetes might be indicated.
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