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- 자료유형
- 학술저널
- 저자정보
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- 대한수의학회 Korean Journal of Veterinary Research(대한수의학회지) Korean Journal of Veterinary Research(구 대한수의학회지) 제59권 제3호
- 발행연도
- 2019.10
- 수록면
- 157 - 160 (4page)
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The production of rmtB-encoded 16S rRNA methylases has emerged as a novel mechanism promoting high-level resistance toward aminoglycosides in Gram-negative bacteria. Between 2015 and 2017, 636 distinct commensal Escherichia (E.) coli isolates were collected from different farms in South Korea to determine the prevalence and molecular characteristics of rmtB. The positive rates of rmtB between all the isolates and amikacin-resistant isolates were 1.1 and 100%, respectively. High-level aminoglycoside resistance could be transferred by conjugation from rmtB-positive donors to higher amikacin-resistance efficacies. This is the first report of 16S rRNA methylase-encoding genes in E. coli isolated from food-producing animals in Korea.
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