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논문 기본 정보

자료유형
학술저널
저자정보
Jiwon Lee (Kyungpook National University) Yongku Kim (Kyungpook National University) Young Min Kim (Kyungpook National University)
저널정보
한국통계학회 CSAM(Communications for Statistical Applications and Methods) CSAM(Communications for Statistical Applications and Methods) 제29권 제3호
발행연도
2022.5
수록면
287 - 299 (13page)

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초록· 키워드

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In radiation epidemiology, the excess relative risk (ERR) model is used to determine the dose–response relationship. In general, the dose-response relationship for the ERR model is assumed to be linear, linear-quadratic, linear-threshold, quadratic, and so on. However, since none of these functions dominate other functions for expressing the dose-response relationship, a Bayesian semiparametric method using splines has recently been proposed. Thus, we improve the Bayesian semiparametric method for the selection of the tuning parameters for splines as the number and location of knots using a Bayesian knot selection method. Equally spaced knots cannot capture the characteristic of radiation exposed dose distribution which is highly skewed in general. Therefore, we propose a nonparametric Bayesian knot selection method based on a Dirichlet process mixture model. Inference of the spline coefficients after obtaining the number and location of knots is performed in the Bayesian framework. We apply this approach to the life span study cohort data from the radiation effects research foundation in Japan, and the results illustrate that the proposed method provides competitive curve estimates for the dose-response curve and relatively stable credible intervals for the curve.

목차

Abstract
1. Introduction
2. Excess relative risk model
3. Bayesian inference
4. Application
5. Concluding remarks
References

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