After the outbreak of COVID-19, the importance of personal safety and hygiene has been emphasized, leading to a rapid change in consumer trends in these days. In response to these trends, industries are focusing on designing with sustainability concepts such as environmentally friendly design, green design and biophilic design, which have emerged as new paradigms that consider natural environments. The purpose of this study is to examines the current status of commercial spaces in domestic that engage in space branding and analyzes the characteristic of biophilic design and analyzes how each commercial space applies biophilic design and explores the direction of commercial space design. The method of this study analysis matrix is derived by utilizing patterns of biophilic design. Through this matrix, visiting and analyzing 3 commercial spaces practicing space branding in domestic. According to the analysis result, the spatial composition is based on elements of biophilic design patterns, such as direct and indirect expressions of nature, natural materials and colors, and ensuring natural lighting in indoor environments. It is suggested that applying natural elements of biophilic design in space branding can enhance the experiential and cognitive aspects of a brand for consumers, providing a differentiated brand experience. Thus, at a time when the market on sustainable commercial spaces should be actively pursued by utilizing biophilic design within commercial spaces.