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논문 기본 정보

자료유형
학술저널
저자정보
Nam-Kyu Kim (Department of Family Practice and Community Health Ajou University School of Medicine Suwon Korea) Min-Ah Jung (Department of Family Practice and Community Health Ajou University School of Medicine Suwon Korea) Seok-Hoon Lee (Department of Family Practice and Community Health Ajou University School of Medicine Suwon Korea) Nam-Seok Joo (Department of Family Practice and Community Health Ajou University School of Medicine Suwon Korea)
저널정보
대한가정의학회 Korean Journal of Family Medicine Korean Journal of Family Medicine 제44권 제1호
발행연도
2023.1
수록면
58 - 63 (6page)
DOI
10.4082/kjfm.22.0131

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Background: Serum thyroid-stimulating hormone (TSH) levels change during body weight reduction. However, the changes that occur during short-term body weight control interventions remain controversial. Thus, this study aimed to evaluate the changes in TSH levels according to body fat reduction.Methods: We performed a 3-month intervention study involving partial meal replacement. Forty-nine participants completed the study. Correlations between changes in TSH levels and other body composition parameters were determined. The subjects were divided into two groups according to their body fat reduction (>1 kg, n=20; <1 kg, n=29). The changes in metabolic parameters, including TSH levels, were compared. For significant values, a multi-variate analysis was performed after adjustment to evaluate the relationship between TSH changes and body fat re-duction.Results: The 3-month intervention caused favorable changes in body proportions and metabolic parameters. TSH levels changed significantly only after changes in total body fat, showing a partial correlation. Changes in TSH levels were significantly different between groups (P=0.014). Moreover, the change in TSH levels was significantly differ-ent after adjustment (P=0.012).Conclusion: A body fat reduction, especially >1 kg, can reduce serum TSH concentrations in subjects with meta-bolic syndrome after short-term body weight intervention.

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