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논문 기본 정보

자료유형
학술저널
저자정보
So Joon Myeong (College of Medicine Yeungnam University Daegu Korea.) Park Ji Ho (College of Medicine Yeungnam University Daegu Korea.) Kim Jin Gyeong (College of Medicine Yeungnam University Daegu Korea.) Park Il Rae (Division of Endocrinology and Metabolism Department of Internal Medicine Yeungnam University College of Medicine Daegu Korea.) Ha Eun Yeong (Division of Endocrinology and Metabolism Department of Internal Medicine Yeungnam University College of Medicine Daegu Korea.) Chung Seung Min (Division of Endocrinology and Metabolism Department of Internal Medicine Yeungnam University College of Medicine Daegu Korea.) Moon Jun Sung (Division of Endocrinology and Metabolism Department of Internal Medicine Yeungnam University College of Medicine Daegu Korea.) Park Chul Hyun (Department of Orthopedic Surgery Yeungnam University College of Medicine Daegu Korea.) Yun Woo-Sung (Department of Surgery Kyungpook National University School of Medicine Daegu Korea.) Kim Tae-Gon (Department of Plastic Surgery Yeungnam University College of Medicine Daegu Korea.) Kim Woong (Division of Cardiology Department of Internal Medicine Yeungnam University College of Medicine Daegu Korea.) Yoon Ji Sung (Division of Endocrinology and Metabolism Department of Internal Medicine Yeungnam University College of Medicine Daegu Korea.) Won Kyu Chang (Division of Endocrinology and Metabolism Department of Internal Medicine Yeungnam University College of Medicine Daegu Korea.) Lee Hyoung Woo (Division of Endocrinology and Metabolism Department of Internal Medicine Yeungnam University College of Medicine Daegu Korea.)
저널정보
대한의학회 Journal of Korean Medical Science Journal of Korean Medical Science Vol.38 No.21
발행연도
2023.5
수록면
1 - 7 (7page)
DOI
10.3346/jkms.2023.38.e160

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We assessed the risk factors for major amputation of diabetic foot ulcers (DFUs) in patients with diabetic kidney disease (DKD) stages 3b–5. For DFU assessment, in addition to DFU location and presence of infection, ischemia, and neuropathy, vascular calcification was assessed using the medial arterial calcification (MAC) score. Of 210 patients, 26 (12.4%) underwent major amputations. Only the location and extension of DFU, represented by Texas grade differed between the minor and major amputation groups. However, after adjusting for covariates, ulcer location of mid- or hindfoot (vs. forefoot, odds ratio [OR] = 3.27), Texas grades 2 or 3 (vs. grade 0, OR = 5.78), and severe MAC (vs. no MAC, OR = 4.46) was an independent risk factor for major amputation (all P < 0.05). The current use of antiplatelets was a possible protective factor for major amputations (OR = 0.37, P = 0.055). In conclusion, DFU with severe MAC is associated with major amputation in patients with DKD.

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