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논문 기본 정보

자료유형
학술저널
저자정보
Hironori Koga (Division of Gastroenterology Department of Medicine Kurume University School of Medicine Kurume; Liver Cancer Research Division Research Center for Innovative Cancer Therapy Kurume University) Hideki Iwamoto (Division of Gastroenterology Department of Medicine Kurume University School of Medicine Kurume; Liver Cancer Research Division Research Center for Innovative Cancer Therapy Kurume University) Hiroyuki Suzuki (Division of Gastroenterology Department of Medicine Kurume University School of Medicine Kurume; Liver Cancer Research Division Research Center for Innovative Cancer Therapy Kurume University) Shigeo Shimose (Division of Gastroenterology Department of Medicine Kurume University School of Medicine) Masahito Nakano (Division of Gastroenterology Department of Medicine Kurume University School of Medicine) Takumi Kawaguchi (Division of Gastroenterology Department of Medicine Kurume University School of Medicine)
저널정보
대한간학회 Clinical and Molecular Hepatology Clinical and Molecular Hepatology 제29권 제2호
발행연도
2023.4
수록면
242 - 251 (10page)

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Striking advances in systemic therapy for unresectable advanced hepatocellular carcinoma (HCC) have improved the average prognosis of patients with HCC. As a result, the guidelines for the treatment of HCC have changed significantly. However, various issues have emerged in clinical practice. First, there is no established biomarker that can predict response to systemic therapy. Second, there is no established treatment regimen after primary systemic therapy, including combined immunotherapy. Third, there is no established treatment regimen for intermediate-stage HCC. These points make the current guidelines ambiguous. In this review, we present the Japanese guidelines for the diagnosis and treatment of HCC based on the latest evidence; introduce various efforts mainly in Japanese real-life practice to update these guidelines; and present our perspectives on future guidelines.

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