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자료유형
학술저널
저자정보
이근우 (Department of Ophthalmology Daegu Catholic University School of Medicine Daegu Korea) 이철호 (Department of Thoracic and Cardiovascular Surgery Daegu Catholic University School of Medicine Daegu Korea) Seong Gyu Kim (Division of Nephrology Department of Internal Medicine Daegu Catholic University School of Medicine Daegu Korea)
저널정보
영남대학교 의과대학 Journal of Yeungnam Medical Science Journal of Yeungnam Medical Science 제40권 제2호
발행연도
2023.4
수록면
146 - 155 (10page)
DOI
10.12701/jyms.2022.00206

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Background: Despite the recent increasing trend in the prevalence of type 2 diabetes among older individuals, the relationship between diabetic retinopathy (DR) and chronic kidney disease (CKD) in these patients remains unclear. This study investigated the severity of renal dysfunction according to the degree of DR in older patients with type 2 diabetes. Methods: A total of 116 patients with diabetes and CKD stage ≥3 who visited both the nephrology and ophthalmology outpatient departments between July 2021 and January 2022 were screened. There were 53 patients in the no DR group, 20 in the nonproliferative DR (NPDR) group, and 43 in the proliferative DR (PDR) group. Results: DR severity was related to the deterioration of renal function. The proportion of patients with advanced CKD significantly increased with DR severity (p for trend <0.001). In the multivariate regression model adjusted for age of ≥80 years, male sex, poorly controlled diabetes, macroalbuminuria, insulin use, diabetes duration of ≥10 years, cerebrovascular accident, hypertension, hyperlipidemia, and cardiovascular disease history, the odds ratio compared with the no DR group was approximately 4.6 for the NPDR group and approximately 11.8 for the PDR group, which were both statistically significant (p=0.025 and p<0.001, respectively). Conclusion: DR severity in older patients with diabetes may be associated with deterioration of renal function and high prevalence of advanced CKD. Therefore, periodic examination for DR in older patients with diabetes is important for predicting renal function deterioration and CKD progression.

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