지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2024.6
- 수록면
- 134 - 142 (9page)
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초록· 키워드
오류제보하기
Non-baumannii Acinetobacter species are increasingly prevalent as opportunistic pathogens in the hospitals worldwide. However, the current information of epidemiology and antimicrobial susceptibility of non-baumannii Acinetobacter species is limited in Korea. This study investigated the species distribution, antimicrobial susceptibility, and carbapenem resistance mechanisms of 65 non-baumannii Acinetobacter isolates from three Korean hospitals during 2017 to 2020. Sixteen different Acinetobacter species were identified. Among them, A. ursingii (n = 16), A. junii (n = 11), and A. nosocomialis (n = 9) were prevalent, accounting for 55.4% of the isolates. A half (50.8%) of non-baumannii Acinetobacter isolates were susceptible to all antimicrobial agents tested. Non-baumannii Acinetobacter isolates exhibited the highest resistance rate to piperacillin (26.2%), whereas no isolates were resistant to minocycline and tigecycline. Seven isolates were resistant to carbapenems by the production of carbapenemases. Ambler class B (bla<SUB>NDM-1</SUB> and bla<SUB>VIM-2</SUB>) and class D carbapenemase genes (bla<SUB>OXA-23</SUB>, bla<SUB>OXA-58</SUB>, bla<SUB>OXA-211</SUB>, and bla<SUB>OXA-213</SUB>) were detected. Three isolates carried two or more carbapenemase genes. One A. calcoaceticus isolate co-carried bla<SUB>VOXA-58</SUB>, bla<SUB>OXA-213</SUB><SUB></SUB>, and bla<SUB>NDM-1</SUB>. In conclusion, this study provides new insights into antimicrobial susceptibility and carbapenem resistance mechanisms of Korean non-baumannii Acinetobacter species. The spread of carbapenem resistance genes should be carefully monitored among non-baumannii Acinetobacter species.
목차
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
REFERENCES
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