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논문 기본 정보

자료유형
학술저널
저자정보
홍종원 (연세대학교) 김요한 (연세대학교) 최윤락 (연세대학교) 백우열 (연세대학교) 서영철 (연세대학교) 오원택 (연세대학교) 조재용 (연세대학교) 이상철 (연세대학교) 류향주 (연세대학교) 전경옥 (연세대학교) 이원재 (연세대학교)
저널정보
연세대학교 의과대학 Yonsei Medical Journal Yonsei Medical Journal Vol.65 No.2
발행연도
2024.2
수록면
108 - 119 (12page)
DOI
10.3349/ymj.2023.0365

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Purpose: With the revision of the Organ and Transplantation Act in 2018, the hand has become legal as an area of transplantable organs in Korea. In January 2021, the first hand allotransplantation since legalization was successfully performed, and we have per formed a total of three successful hand transplantation since then. By comparing and incorporating our experiences, this study aimed to provide a comprehensive reconstructive solution for hand amputation in Korea. Materials and Methods: Recipients were selected through a structured preoperative evaluation, and hand transplantations were performed at the distal forearm level. Postoperatively, patients were treated with three-drug immunosuppressive regimen, and func tional outcomes were monitored. Results: The hand transplantations were performed without intraoperative complications. All patients had partial skin necrosis and underwent additional surgical procedures in 2 months after transplantation. After additional operations, no further severe complications were observed. Also, patients developed acute rejection within 3 months of surgery, but all resolved within 2 weeks after steroid pulse therapy. Motor and sensory function improved dramatically, and patients were very satisfied with the appear ance and function of their transplanted hands. Conclusion: Hand transplantation is a viable reconstructive option, and patients have shown positive functional and psychologi cal outcomes. Although this study has limitations, such as the small number of patients and short follow-up period, we should fo cus on continued recovery of hand function, and be careful not to develop side effects from immunosuppressive drugs. Through the present study, we will continue to strive for a bright future regarding hand transplantation in Korea.

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