개인구독
소속 기관이 없으신 경우, 개인 정기구독을 하시면 저렴하게
논문을 무제한 열람 이용할 수 있어요.
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2024.2
- 수록면
- 17 - 28 (12page)
이용수
초록· 키워드
오류제보하기
Objectives : This study was conducted to reveal the scientific mechanism of the anti-skin aging activity of Kyung-Ok-Ko(KOK), which is highly useful as a Korean traditional medicine and functional food.
Methods : The skin wrinkle and aging inhibitory activity of KOK was confirmed through in vitro experiments of human dermal fibroblast neonatal cell(HDFn) and in vivo of C. elegans, and hairless mouse(SKH-1).
Results : The amount of the C-terminus of the collagen precursor in the HDFn cell culture medium treated with KOK using an enzymes-linked immunoassay kit. The group treated with KOK 200㎍/㎖ was a 28.3% increase of collagen precursor compared to the control group. KOK showed inhibitory activity of MMP-1 compared to the control group at a concentration of 200㎍/㎖. In addition, KOK 200㎍/㎖ showed significant inhibitory activity of thermal stress and an oxidative stress compared to the control group in C. elegans. Furthermore, KOK showed a concentration-dependent(100㎎/㎏ and 500㎎/㎏) anti-wrinkle formation effect in UV-irradiated hairless mouse(SKH-1). Additionally, when KOK was administered to UV-irradiated hairless mice, an increase in procollagen -1 and -3 genes expression was observed, and mmp-1 and mmp-9 genes, which increase collagen decomposition, decreased with the administration of KOK.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
C. elegans를 이용한 차원별 은나노 독성평가
환경독성보건학회 심포지엄 및 학술대회
2016 .10
-
Autophagy : lessons From C. elegans
한국실험동물학회 학술발표대회 논문집
2015 .08
-
Ginsenosides Rg1 regulate lipid metabolism and temperature adaptation in Caenorhabditis elegans
Journal of Ginseng Research
2023 .07
-
Analysis of high-fat diet-induced inflammatory responses in Rhbdf2 knockout mice
예방수의학회지
2018 .12
-
Effect of Pathogen infection on Caenorhabditis elegans stress response to silver nanoparticle
환경독성보건학회 심포지엄 및 학술대회
2015 .10
-
Toxicological comparison of BPA, BPS, BPF and TMBPF in Caenorhabditis elegans
환경독성보건학회 심포지엄 및 학술대회
2021 .10
-
Biological effects of microplastics in Caenorhabditis elegans
환경독성보건학회 심포지엄 및 학술대회
2022 .05
-
블루베리 듀크 추출물의 예쁜꼬마선충 내의 항산화 효과
생약학회지(Korean Journal of Pharmacognosy)
2017 .09
-
돼지감자꽃의 예쁜꼬마선충 내의 항산화 효과
생약학회지(Korean Journal of Pharmacognosy)
2019 .06
-
The lack of top3β decreases anxiety-like behavior
한국실험동물학회 학술발표대회 논문집
2016 .02
-
High-throughput screening of developmental toxicity of nanomaterials in Caenorhabditis elegans
환경독성보건학회 심포지엄 및 학술대회
2015 .10
-
상황버섯의 예쁜꼬마선충 내의 항산화 효과
생약학회지(Korean Journal of Pharmacognosy)
2019 .12
-
Role of intestinal dysbiosis on Complement C3 deficiency induced constipation in knockout mice
한국실험동물학회 학술발표대회 논문집
2021 .01
-
선씀바귀 Ethyl acetate 분획물의 예쁜 꼬마선충 내의 항산화 효과
생약학회지(Korean Journal of Pharmacognosy)
2023 .12
-
Correlation between gut microbiota dysbiosis and the development of constipation in complement C3 knockout mice
한국실험동물학회 학술발표대회 논문집
2021 .07
-
단삼의 예쁜꼬마선충 내의 항산화 효과
생약학회지(Korean Journal of Pharmacognosy)
2018 .12
-
Longevity and Stress Resistant Property of 6-Gingerol from Zingiber officinale Roscoe in Caenorhabditis elegans
Biomolecules & Therapeutics(구 응용약물학회지)
2018 .01
-
Mechanosensitive Piezo Channel, PEZO-1, regulates food deglutition in C. elegans
한국실험동물학회 학술발표대회 논문집
2022 .01
-
Assessment of oxidative stress caused by anthracene and alkyl-anthracenes in Caenorhabditis elegans
환경독성보건학회 심포지엄 및 학술대회
2016 .06
-
비트 Methanol 추출물의 예쁜 꼬마선충에 대한 항산화 효과
생약학회지(Korean Journal of Pharmacognosy)
2020 .09
최근 본 자료
댓글(0)
0