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논문 기본 정보

자료유형
학술저널
저자정보
Tai Ta-Wei (Dept. of Orthopedics, National Cheng Kung University Hospital, Tainan, Taiwan) Chen Hsuan-Yu (National Taiwan University College of Medicine and National Taiwan University Hospital, Taipei, Taiwan) Shih Chien-An Huang Chun-Feng McCloskey Eugene Lee Joon-Kiong Yeap Swan Sim Cheung Ching-Lung Charatcharoenwitthaya Natthinee Jaisamrarn Unnop Kuptniratsaikul Vilai Yang Rong-Sen Lin Sung-Yen Taguchi Akira Mori Satoshi Li-Yu Julie Ang Seng Bin Chan Ding-Cheng Chan Wai Sin Ng Hou Chen Jung-Fu Tu Shih-Te Chuang Hai-Hua Chang Yin-Fan Chen Fang-Ping Tsai Keh-Sung Ebeling Peter R. Marin Fernando Nistal Rodríguez Francisco Javier Shi Huipeng Hwang Kyu Ri (Seoul Metropolitan Government-Seoul National University Boramae Medical Center) 김광균 (건양대학교) Chung Yoon-Sok (Department of Endocrinology and Metabolism, Ajou University School of Medicine, Suwon 16499, Korea.) Reid Ian R. Chandran Manju Ferrari Serge Lewiecki E Michael Hew Fen Lee Ho-Pham Lan T. Nguyen Tuan Van Nguyen Van Hy Lekamwasam Sarath Pandey Dipendra Bhadada Sanjay Chen Chung-Hwan (Department of Orthopaedics and Orthopaedic Research Center, Kaohsiung Medical University Hospital, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.Department of Orthopae) Hwang Jawl-Shan Wu Chih-Hsing (Dept. of Family Medicine, National Cheng Kung University Hospital & Institute of Geriatrics, Taiwan)
저널정보
대한골다공증학회 Osteoporosis and Sarcopenia English Vol.10 No.1
발행연도
2024.3
수록면
3 - 10 (8page)
DOI
10.1016/j.afos.2024.02.001

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초록· 키워드

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Objectives: This study aimed to present the Asia-Pacific consensus on long-term and sequential therapy for osteoporosis, offering evidence-based recommendations for the effective management of this chronic condition. The primary focus is on achieving optimal fracture prevention through a comprehensive, individualized approach. Methods: A panel of experts convened to develop consensus statements by synthesizing the current literature and leveraging clinical expertise. The review encompassed long-term anti-osteoporosis medication goals, first-line treatments for individuals at very high fracture risk, and the strategic integration of anabolic and antiresorptive agents in sequential therapy approaches. Results: The panelists reached a consensus on 12 statements. Key recommendations included advocating for anabolic agents as the first-line treatment for individuals at very high fracture risk and transitioning to antiresorptive agents following the completion of anabolic therapy. Anabolic therapy remains an option for individuals experiencing new fractures or persistent high fracture risk despite antiresorptive treatment. In cases of inadequate response, the consensus recommended considering a switch to more potent medications. The consensus also addressed the management of medication-related complications, proposing alternatives instead of discontinuation of treatment. Conclusions: This consensus provides a comprehensive, cost-effective strategy for fracture prevention with an emphasis on shared decision-making and the incorporation of country-specific case management systems, such as fracture liaison services. It serves as a valuable guide for healthcare professionals in the Asia-Pacific region, contributing to the ongoing evolution of osteoporosis management.

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