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논문 기본 정보

자료유형
학술저널
저자정보
Suzuki Yugo (Department of Gastroenterology, Toranomon Hospital, Tokyo, Japan) Ochiai Yorinari (Department of Gastroenterology, Toranomon Hospital, Tokyo, Japan) Hosoi Atsuko (Department of Pathology, Toranomon Hospital, Tokyo, Japan) Okamura Takayuki (Department of Gastroenterology, Toranomon Hospital, Tokyo, Japan) Hayasaka Junnosuke (Department of Gastroenterology, Toranomon Hospital, Tokyo, Japan) Mitsunaga Yutaka (Department of Gastroenterology, Toranomon Hospital, Tokyo, Japan) Tanaka Masami (Department of Gastroenterology, Toranomon Hospital, Tokyo, Japan) Odagiri Hiroyuki (Department of Gastroenterology, Toranomon Hospital, Tokyo, Japan) Nomura Kosuke (Department of Gastroenterology, Toranomon Hospital, Tokyo, Japan) Yamashita Satoshi (Department of Gastroenterology, Toranomon Hospital, Tokyo, Japan) Matsui Akira (Department of Gastroenterology, Toranomon Hospital, Tokyo, Japan) Kikuchi Daisuke (Department of Gastroenterology, Toranomon Hospital, Tokyo, Japan) Ohashi Kenichi (Department of Human Pathology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan) Hoteya Shu (Department of Gastroenterology, Toranomon Hospital, Tokyo, Japan)
저널정보
거트앤리버 발행위원회 Gut and Liver Gut and Liver Vol.18 No.1
발행연도
2024.1
수록면
50 - 59 (10page)
DOI
10.5009/gnl220490

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초록· 키워드

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Background/Aims: Asymptomatic esophageal eosinophilia (aEE) is considered to be a potential precursor of eosinophilic esophagitis (EoE). However, there are few clinical parameters that can be used to evaluate the disease. Therefore, we aimed to clarify the factors involved in the symptoms of EoE by examining the clinicopathological differences between aEE and EoE. Methods: We reviewed 41 patients with esophageal eosinophilia who underwent endoscopic ultrasonography and high-resolution manometry. They were divided into the aEE group (n=16) and the EoE group (n=25) using the Frequency Scale for the Symptoms of Gastroesophageal Reflux Disease score. The patients’ clinicopathological findings were collected and examined. Results: The median Frequency Scale for the Symptoms of Gastroesophageal Reflux Disease score was 3.0 in the aEE group and 10.0 in the EoE group. There was no significant difference in patient characteristics, endoscopic findings and pathological findings. The cutoff value for wall thickening was 3.13 mm for the total esophageal wall thickness and 2.30 mm for the thickness from the surface to the muscular layer (total esophageal wall thickness: 84.0% sensitivity, 75.0% specificity; thickness from the surface to the muscular layer: 84.0% sensitivity, 68.7% specificity). The high-resolution manometry study was abnormal in seven patients (43.8%) in the aEE group and in 12 (48.0%) in the EoE group. The contractile front velocity was slower in the EoE group (p=0.026). Conclusions: The esophageal wall thickening in the lower portion of the esophagus is an important clinical factors related to the symptoms in patients with EoE.

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