지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 환경독성보건학회 Environmental Analysis Health and Toxicology Environmental Analysis Health and Toxicology Vol.39 No.2
- 발행연도
- 2024.6
- 수록면
- 125 - 137 (13page)
이용수
초록· 키워드
오류제보하기
The global occurrence of microplastics and their poorly understood health implications underscore the need for scientific investigation. This study aimed to assess the effects of microplastics exposure. Twenty-five (25) albino rats (Rattus norvegicus) were divided into five (5) groups, each consisting of five rats. Group 1 (the negative control) received normal feed; group 2 (the positive control) was administered a 10 % lead acetate solution; and groups 3, 4, and 5 were administered 1 %, 5 %, and 10 % microplastic solutions, respectively. The rats were monitored for 28 days, after which blood samples were taken for hematological and lipid profiles as well as liver and kidney function parameters. The results revealed dose-dependent significant (p < 0.05) alterations in the health indices of the treated rats and the positive control compared with the negative control. Specifically, the hematological parameters, including the white blood cells (WBC) and its subtypes, were reduced, indicating immunosuppressive effects, and the red blood cells (RBC), hemoglobin (HGB), hematocrit (HCT), platelets, mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), and mean corpuscular hemoglobin concentration (MCHC) were reduced, indicating anemia. The 1 % and 5 % microplastic solutions raised the lipid profiles of the treated rats, including total cholesterol (TC), triglycerides (TG), high-density lipoprotein (HDL), and low-density lipoprotein (LDL), while the 10 % concentration decreased them, causing hyperlipidemia and hypolipidemia, respectively. The liver function parameters, including total protein (TP), albumin (ALB), aspartate transaminase (AST), alanine transaminase (ALT), and alkaline phosphatase (ALP), were elevated, indicating liver damage. Elevation of kidney function parameters, including sodium ion (Na+), potassium ion (K+), chloride ion (Cl-), urea, and creatinine (CRT), were noticed, suggesting kidney injuries. It can be inferred from these results that microplastics are toxic. Hence, human exposure to microplastics should be reduced to a minimum.
목차
Abstract
Introduction
Materials and Methods
Results
Discussion
Conclusions
References
참고문헌 (60)
참고문헌 신청
Karbalaei S, Hanachi P, Rafiee G, Seifori P, Walker TR. Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos. J Hazard Mater 2021;403:123980. https://doi.org/10.1016/j.jhazmat.2020.123980
Tursi A, Baratta M, Easton T, Chatzisymeon E, Chidichimo F, De Biase M, et al. Microplastics in aquatic systems, a comprehensive review: origination, accumulation, impact, and removal technologies. RSC Advance 2022;12(44):28318-28340. https://doi.org/10.1039/D2RA04713F
Yong CQY, Valiyaveettil S, Tang BL. Toxicity of microplastics and nanoplastics in mammalian systems. International Journal of Environmental Research and Public Health 2020;17(5):1509. https://doi.org/10.3390/ijerph17051509
Wang W, Ge J, Yu X. Bioavailability and toxicity of microplastics to fish species: A review. Ecotoxicology and Environmental Safety 2020;189:109913. https://doi.org/10.1016/j.ecoenv.2019.109913
Mohammed JS, Mustapha Y, Him MA, Danladi ZN. Assessment of cytogenotoxicity of plastic industrial effluent using Allium cepa root tip cells. International Journal of Cell Biology 2023;2023:5161017. https://doi.org/10.1155/2023/5161017
Tursi A, Baratta M, Easton T, Chatzisymeon E, Chidichimo F, De Biase M, et al. Microplastics in aquatic systems, a comprehensive review: origination, accumulation, impact, and removal technologies. RSC Advance 2022;12(44):28318-28340. https://doi.org/10.1039/D2RA04713F
Yong CQY, Valiyaveettil S, Tang BL. Toxicity of microplastics and nanoplastics in mammalian systems. International Journal of Environmental Research and Public Health 2020;17(5):1509. https://doi.org/10.3390/ijerph17051509
Wang W, Ge J, Yu X. Bioavailability and toxicity of microplastics to fish species: A review. Ecotoxicology and Environmental Safety 2020;189:109913. https://doi.org/10.1016/j.ecoenv.2019.109913
Mohammed JS, Mustapha Y, Him MA, Danladi ZN. Assessment of cytogenotoxicity of plastic industrial effluent using Allium cepa root tip cells. International Journal of Cell Biology 2023;2023:5161017. https://doi.org/10.1155/2023/5161017
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Impact of polystyrene microplastic exposure on lipid profile and oxidative stress status of male and female Wistar rats
Environmental Analysis Health and Toxicology
2022 .09
-
Health Effects of Microplastic Exposures: Current Issues and Perspectives in South Korea
Yonsei Medical Journal
2023 .05
-
Monitoring and assessing human exposure to microplastics via foods consumption
환경독성보건학회 심포지엄 및 학술대회
2022 .05
-
Biodistribution study of orally administered microplastics: PET/CT study
한국실험동물학회 학술발표대회 논문집
2021 .07
-
Chronic toxic effects of polystyrene microplastics on reproductive parameters of male rats
Environmental Analysis Health and Toxicology
2022 .06
-
미세플라스틱의 개념과 해양에서의 발생, 이동, 생물영향 및 관리대책
한국환경보건학회지
2020 .10
-
Microplastics in food containers and biological samples
환경독성보건학회 심포지엄 및 학술대회
2021 .05
-
Microplastics: an invisible danger to human brain health - neurological hazards of microplastic accumulation in the brain
한국실험동물학회 학술발표대회 논문집
2025 .02
-
A Study on the Distributional patterns of Microplastics in Southern Sea of Korea
환경독성보건학회 심포지엄 및 학술대회
2021 .05
-
Evaluation of 28-day repeated oral dose toxicity of aluminum chloride in rats
한국실험동물학회 학술발표대회 논문집
2021 .01
-
Evaluation of 28-day repeated oral dose toxicity of aluminum chloride in rats
한국실험동물학회 학술발표대회 논문집
2021 .07
-
Effects of microplastic on the animal nervous system
한국실험동물학회 학술발표대회 논문집
2025 .02
-
생활환경 미세플라스틱의 노출평가를 위한 노출계수 도출 방안 연구
환경독성보건학회 심포지엄 및 학술대회
2022 .10
-
Public behavior and awareness of mask litter as microplastic source
환경독성보건학회 심포지엄 및 학술대회
2023 .11
-
Complex effect of microplastics on development and reproduction of plants
환경독성보건학회 심포지엄 및 학술대회
2021 .10
-
Quantification of microplastics in mouse liver using pyrolysis-gas chromatography/mass spectrometry
환경독성보건학회 심포지엄 및 학술대회
2021 .10
-
Protective effects of natural extracts on acetaminophen-induced liver and kidney damage in rats
한국실험동물학회 학술발표대회 논문집
2018 .07
-
Acute Variation of Hematological Parameters during 622 km Ultra-Marathon
대한의생명과학회지
2017 .09
-
폴리에틸렌 미세플라스틱의 임신 마우스 위내투여에 따른 모체 및 신생자 독성평가
한국환경보건학회지
2021 .10
-
Study on the emission characteristics of microplastics during laundry processes
환경독성보건학회 심포지엄 및 학술대회
2021 .10
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-151-24-02-090645117