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논문 기본 정보

자료유형
학술저널
저자정보
Yusuke Toyohara (Department of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan) Kenbun Sone (Department of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan) Katsuhiko Noda (SIOS Technology Inc.) Kaname Yoshida (SIOS Technology Inc.) Shimpei Kato (Department of Radiology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan) Masafumi Kaiume (Department of Radiology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan) Ayumi Taguchi (Department of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan) Ryo Kurokawa (Department of Radiology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan) Yutaka Osuga (Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan)
저널정보
대한부인종양학회 Journal of Gynecologic Oncology Journal of Gynecologic Oncology Vol.35 No.3
발행연도
2024.5
수록면
1 - 13 (13page)
DOI
https://doi.org/10.3802/jgo.2024.35.e24

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초록· 키워드

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Objective: Magnetic resonance imaging (MRI) is efficient for the diagnosis of preoperativeuterine sarcoma; however, misdiagnoses may occur. In this study, we developed a newartificial intelligence (AI) system to overcome the limitations of requiring specialists tomanually process datasets and a large amount of computer resources. Methods: The AI system comprises a tumor image filter, which extracts MRI slices containingtumors, and sarcoma evaluator, which diagnoses uterine sarcomas. We used 15 types of MRIpatient sequences to train deep neural network (DNN) models used by tumor filter and sarcomaevaluator with 8 cross-validation sets. We implemented tumor filter and sarcoma evaluatorusing ensemble prediction technique with 9 DNN models. Ten tumor filters and sarcomaevaluator sets were developed to evaluate fluctuation accuracy. Finally, AutoDiag-AI was used toevaluate the new validation dataset, including 8 cases of sarcomas and 24 leiomyomas. Results: Tumor image filter and sarcoma evaluator accuracies were 92.68% and 90.50%,respectively. AutoDiag-AI with the original dataset accuracy was 89.32%, with 90.47%sensitivity and 88.95% specificity, whereas AutoDiag-AI with the new validation datasetaccuracy was 92.44%, with 92.25% sensitivity and 92.50% specificity. Conclusion: Our newly established AI system automatically extracts tumor sites from MRIimages and diagnoses them as uterine sarcomas without human inter vention. Its accuracyis comparable to that of a radiologist. With further validation, the system could be appliedfor diagnosis of other diseases. Further improvement of the system's accuracy may enable itsclinical application in the future.

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