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논문 기본 정보

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학술저널
저자정보
Deniz Rabia (Department of Rheumatology, Başakşehir Çam and Sakura City Hospital, University of Health Sciences, Istanbul, Turkey) Hacımurtazaoğlu-Demir Gülşah (Department of Internal Medicine, University of Health Sciences Bağcılar Education and Research Hospital, Istanbul, Turkey) Karaalioğlu Bilgin (Department of Rheumatology, Başakşehir Çam and Sakura City Hospital, University of Health Sciences, Istanbul, Turkey) Özgür Duygu Sevinç (Department of Rheumatology, Başakşehir Çam and Sakura City Hospital, University of Health Sciences, Istanbul, Turkey) Akkuzu Gamze (Department of Rheumatology, Başakşehir Çam and Sakura City Hospital, University of Health Sciences, Istanbul, Turkey) Yıldırım Fatih (Department of Rheumatology, Başakşehir Çam and Sakura City Hospital, University of Health Sciences, Istanbul, Turkey) Bes Cemal (Department of Rheumatology, Başakşehir Çam and Sakura City Hospital, University of Health Sciences, Istanbul, Turkey)
저널정보
대한류마티스학회 대한류마티스학회지 Journal of Rheumatic Diseases Vol.31 No.2
발행연도
2024.4
수록면
116 - 119 (4page)
DOI
10.4078/jrd.2023.0052

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The triad of ascites, pleural effusion, and elevated cancer antigen-125 (CA-125) levels in the absence of ovarian malignancy in systemic lupus erythematosus patients is specifically named pseudo-pseudo Meigs’ syndrome (PPMS) or Tjalma syndrome. In this case we reported a 33 years female patient with pleural effusion lasting for 3 years and new onset progressive massive ascites and increased level of CA-125. After she was evaluated for an underlying benign and malign ovarian tumor or any other malignancies, serologic tests were requested with respect to progressive renal dysfunction, proteinuria, lymphopenia, anemia, and effusion. She was diagnosed with systemic lupus erythamatosus (SLE) and renal biopsy showed class-V lupus nephritis. Immunosuppressive treatment led to improvement in both SLE activity and components of PPMS, including massive ascites and pleural effusion and without the need of diuretics. Co-existence of unexplained CA-125 increase, pleural effusion, and ascites might be related to PPMS and detailed examination to exclude malignancy and early and effective treatment of SLE are the mainstay of management.

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