지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2024.12
- 수록면
- 20 - 34 (15page)
- DOI
- 10.17262/KJPH.2024.12.61.2.18
이용수
초록· 키워드
오류제보하기
Background: Major ophthalmic disease includes Age-Related Macular Degeneration, Glaucoma and Diabetic retinopathy and they can lead to blindness. There are former studies only for each respective disease. If we can find common risk factors for these 3 diseases it can lay the ground to discuss preventive and diagnostic strategies for all 3 diseases at once.
Methods: The sample cohort DB in the National Health Insurance System was used for this study excluding those who already were diagnosed with three diseases from 2008 to 2009, which was set as a wash-out period.
Based on adjusted various chronic disease variables and the variables identified as significant risk factors in the previous studies, the common high-risk group was found from Cox proportional hazard regression analysis.
Results: As a result of examining the incidence of the three diseases, the incidence rate of women was statistically significantly higher than that of men (HR, 1.20; 95% CI, 1.14-1.25; p=<.001). There were also significant differences in age groups, with the increasing risk per age until the age of 80 (p=<.001). Fasting blood glucose (HR, 1.01; 95% CI, 1.01-1.01; p=<.001) and systolic blood pressure (HR, 1.01; 95% CI, 1.01- 1.01; p=<.001), and diastolic blood pressure (HR, 1.00; 95% CI, 1.00-1.01; p=<.001) were all increased when the values were increased, and taking hypertension medications (HR, 2.21; 95% CI, 2.10-2.31; p=<.001) and diabetes medications (HR, 6.61; 95% CI, 6.28-6.96; p=<.001) were also found to have a significant effect. The highest risk group was identified as women in their 70s (70 to 79 years old), who were taking diabetes medications, but were not controlled diabetes, and were on hypertension medications.
Conclusion: In this study, we can conclude that identified high-risk group has a higher hazard ratio. As Korea is close to the super-aging society which has more prevalence rate of Age-Related Macular Degeneration, Glaucoma and Diabetic retinopathy and higher treatment burden, it is expected to increase quality of life of the patients and less burden of national treatment cost if the discussion for preventive and diagnostic strategies for all 3 diseases could be made based on this study.
Methods: The sample cohort DB in the National Health Insurance System was used for this study excluding those who already were diagnosed with three diseases from 2008 to 2009, which was set as a wash-out period.
Based on adjusted various chronic disease variables and the variables identified as significant risk factors in the previous studies, the common high-risk group was found from Cox proportional hazard regression analysis.
Results: As a result of examining the incidence of the three diseases, the incidence rate of women was statistically significantly higher than that of men (HR, 1.20; 95% CI, 1.14-1.25; p=<.001). There were also significant differences in age groups, with the increasing risk per age until the age of 80 (p=<.001). Fasting blood glucose (HR, 1.01; 95% CI, 1.01-1.01; p=<.001) and systolic blood pressure (HR, 1.01; 95% CI, 1.01- 1.01; p=<.001), and diastolic blood pressure (HR, 1.00; 95% CI, 1.00-1.01; p=<.001) were all increased when the values were increased, and taking hypertension medications (HR, 2.21; 95% CI, 2.10-2.31; p=<.001) and diabetes medications (HR, 6.61; 95% CI, 6.28-6.96; p=<.001) were also found to have a significant effect. The highest risk group was identified as women in their 70s (70 to 79 years old), who were taking diabetes medications, but were not controlled diabetes, and were on hypertension medications.
Conclusion: In this study, we can conclude that identified high-risk group has a higher hazard ratio. As Korea is close to the super-aging society which has more prevalence rate of Age-Related Macular Degeneration, Glaucoma and Diabetic retinopathy and higher treatment burden, it is expected to increase quality of life of the patients and less burden of national treatment cost if the discussion for preventive and diagnostic strategies for all 3 diseases could be made based on this study.
목차
Abstract
Introduction
Methods
Results
Discussion
Conclusion
References
참고문헌 (0)
참고문헌 신청이 논문과 함께 이용한 논문
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-151-25-02-091257330