Purpose: This study examined the relationships between nursing stress related to life sustaining treatment, moral identity, leisure satisfaction, and burnout among intensive care unit (ICU) nurses. The mediating effects of moral identity and leisure satisfaction on the relationship between nursing stress related to life sustaining treatment and burnout were also investigated. Methods: A descriptive survey was conducted between August 1 and September 30, 2024. The questionnaire survey was administered to 200 ICU nurses with over six months of experience at two university hospitals in City B. Analyses included t-tests, ANOVA, Scheffé’s test, Pearson's correlation, and Hayes' Process Macro Model 4. Results: Burnout was found negatively associated with moral identity (r=-.19, p=.012) and leisure satisfaction (r=-.19, p=.009), while nursing stress related to life sustaining treatment shown to be positively associated with burnout (r=.17, p=.022). Moral identity and leisure satisfaction mediated the relationship between nursing stress related to life sustaining treatment and burnout. Conclusion: To prevent burnout among ICU nurses, it is suggested that strategies should focus on enhancing moral identity and leisure satisfaction.