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논문 기본 정보

자료유형
학술저널
저자정보
Daichi Maeda (Juntendo University Graduate School of Medicine) Yudai Fujimoto (Juntendo University Graduate School of Medicine) Taisuke Nakade (Juntendo University Graduate School of Medicine) Takuro Abe (Saitama Medical Center) Shiro Ishihara (Saitama Medical Center) Kentaro Jujo (Saitama Medical Center) Yuya Matsue (Juntendo University Graduate School of Medicine)
저널정보
대한심장학회 Korean Circulation Journal Korean Circulation Journal Vol.54 No.7
발행연도
2024.7
수록면
363 - 381 (19page)
DOI
https://doi.org/10.4070/kcj.2024.0089

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With global aging, the number of patients with heart failure has increased markedly. Heart failure is a complex condition intricately associated with aging, organ damage, frailty, and cognitive decline, resulting in a poor prognosis. The relationship among frailty, sarcopenia, cachexia, malnutrition, and heart failure has recently received considerable attention. Although these conditions are distinct, they often exhibit a remarkably close relationship. Overlapping diagnostic criteria have been observed in the recently proposed guidelines and position statements, suggesting that several of these conditions may coexist in patients with heart failure. Therefore, a comprehensive understanding of these conditions is essential, and interventions must not only target these conditions individually, but also provide comprehensive management strategies. This review article provides an overview of the epidemiology, diagnostic methods, overlap, and prognosis of frailty, sarcopenia, cachexia, and malnutrition in patients with heart failure, incorporating insights from the FRAGILE-HF study data. Additionally, based on existing literature, this article discusses the impact of these conditions on the effectiveness of guideline-directed medical therapy for patients with heart failure. While recognizing these conditions early and promptly implementing interventions may be advantageous, further data, particularly from well-powered, large-scale, randomized controlled trials, are necessary to refine personalized treatment strategies for patients with heart failure.

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